Update From Seattle 2017.

Slides:



Advertisements
Similar presentations
Hepatitis web study Hepatitis web study Sofosbuvir + Ribavirin in HCV-HIV Coinfection: HCV GT 1,2,3,4 PHOTON-2 Trial Phase 3 Molina JM, et al. IAC. 2014;
Advertisements

Update on the HCV Antiviral Pipeline Todd S. Wills, MD SPNS HCV Treatment Expansion Initiative Evaluation and Technical Assistance Center Infectious Disease.
NEXT STEPS IN THE GLOBAL TREATMENT SIMPLIFICATION AGENDA THE ROLE OF PARTNERSHIPS Nathan Ford Department HIV and Global Hepatitis Programme WHO, Geneva.
ARE PAN-GENOTYPIC THERAPIES READY FOR PRIME TIME? 3 Rd International HIV/Hepatitis Coinfection Meeting Durban SA Marina B. Klein, MD, MSc FRCP(C) Chronic.
Phase 3 Treatment-Naïve and Treatment-Experienced
Where Are We on the Path to Elimination of Chronic Hepatitis C?
CROI 2017 Report Back: Liver Disease and HIV
Pipeline & HCV UK-CAB 31 January 2009.
Sofosbuvir-Velpatasvir in HIV-HCV Coinfected Patients ASTRAL-5
Clinical outcome after SVR: Veterans Affairs
Chronic HCV Infection and CKD
HIV/HCV Co-Infection Case
Managing Bleeds in Patients Anticoagulated With Warfarin and Other Agents.
This program will include a discussion of off-label treatment and investigational agents not approved by the FDA for use in the United States.
Starting Strong: Initial Evaluation of the Patient With HCV
Essential Updates in Atopic Dermatitis:
Introduction. Looking Beyond HIV Infection: CCR5 Blockade as an Immunomodulatory Concept 
HCV Infection in the United States: What Are We Dealing With?
State of the Art in HCC: Immune Checkpoint Modulation
Dual Antiretroviral Therapy
World Epidemiology. Are HIV and Other Chronic Diseases Models Applicable to Viral Hepatitis? Focus on HCV.
The Aging Liver in the Aging HIV and HCV Patients
Advances in HIV Care.
HCV Care in Unique Patient Populations
HIV Management: An Update on the Latest EACS Guidelines
Extended Half-life Factor Products in the Management of Hemophilia
Treating HIV Infection:
Selecting NOACs for High-Risk Patients
HCV Screening.
مدیریت امور آزمایشگاهها دانشگاه علوم پزشکی کاشان
Translating Emerging HIV Data Into Clinical Practice
Asthma and Atopic Comorbidities
Evaluation of the Patient With HCV Infection
What Does the Primary Care Physician Need to Know About Chronic Hepatitis C?
HCV Protease Inhibitors in Clinical Practice
Is it Time for a Paradigm Change in HIV Management?
Risk of de novo Hepatocellular Carcinoma after HCV Treatment with Direct-Acting Antivirals Liver Cancer - DOI: / Fig. 1. Flowchart of included.
AF and PCI in Practice.
PrEP.
HIV : New Agents, New Strategies
New Agents, New Regimens, New Strategies
Initiating Pre-exposure Prophylaxis The PrEP Checklist
Rheumatoid Arthritis 2015 Guidelines What's New? What's Different?
Care of the Treatment-naive Patient With HCV/HIV Coinfection
Next Generation Capsid Inhibitor: GS–CA1
The JAK-STAT Pathway and Graft-vs-Host Disease
How to Effectively Manage Patients With Cutaneous Squamous Cell Carcinoma.
Clinical outcome after SVR: ANRS CO22 HEPATHER
PrEP Ongoing Care.
Investigational Approaches to Antiretroviral Therapy
Factor Xa Inhibitors in PAD
Advances in the Treatment of HCV Genotype 3 and HIV/HCV Coinfection
Cancer-Associated Thrombosis
Managing Age-Related Clinical Issues in Hemophilia
Extended Half-life Factor Products in the Management of Hemophilia
HCV Protease Inhibitors in Clinical Practice
Optimizing Joint Health in Hemophilia
HIV Update 2018: A Front Row Seat
Elimination of Hepatitis C in Individuals With HIV Infection
Reconciling Aging With HIV
Improving Overall Health
What Does the Future Hold and What Will It Mean for Patients?
Checkpoint Inhibitors in First-Line Advanced NSCLC
Tailoring Therapy in the Newly Diagnosed Patient With CLL
Updates From CROI 2019: Treatment of HIV and Its Complications
Incidence of HCC after HCV treatment with DAAs: ERCHIVES
MS, Age, and Immune Function
HIV and HCV coinfection in solid organ transplantation
Risk Stratification in MDS
Characterizing Virological Suppression in Today's Treatment Paradigm
Presentation transcript:

Update From Seattle 2017

Update From Seattle 2017 (cont)

HIV Treatment

Dual ART – DTG + RPV SWORD-1 and SWORD-2

Dual ART – DTG + RPV SWORD-1 and SWORD-2 (cont)

Dual ART – CAB + RPV LATTE Wk 144 Results

Dual ART – CAB + RPV LATTE Wk 144 Results (cont)

Dual ART – CAB + RPV LATTE Wk 144 Results (cont)

Initial ART With TAF vs TDF Wk 144 Follow-Up

Dual ART LAMIDOL Study (ANRS 167)

Investigational Agent – Bictegravir Phase 2 Study Results

Investigational Agent – Doravirine DRIVE Study – Wk 48 Results

Investigational Agent – Doravirine DRIVE Study – Wk 48 Results (cont)

Investigational Agent – Doravirine DRIVE Study – Wk 48 Results (cont)

Investigational Agent – Capsid Inhibitor GS-CA1

Additional Investigational Agents Phase 1 or Phase 2

Comorbidities and Aging

Unrestricted Access of DAA Agents Rapid Uptake in Patients With HIV/HCV Coinfection

DAA Agents Treatment as Prevention in MSM?

Risk of HCC in Patients With HIV/HCV Coinfection After SVR (HCV) GEHEP-002 Cohort

Risk of HCC in Patients With HIV/HCV Coinfection After SVR GEHEP-002 Cohort (cont)

Risk of HCC in Patients With HIV/HCV Coinfection After SVR GEHEP-002 Cohort (cont)

Hepatic Steatosis The STERAL Study

Hepatic Steatosis The STERAL Study (cont) – Wk 48 Results

BMI and Risk for SNAEs

BMI and Risk for SNAEs (cont)

Aging and Frailty The ALIVE Cohort

Aging and Frailty The ALIVE Cohort (cont)

Summary and Clinical Implications

Abbreviations

Abbreviations (cont)

Abbreviations (cont)