Imported Stem Cells Strike against Stroke

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Presentation transcript:

Imported Stem Cells Strike against Stroke Sophie Péron, Benedikt Berninger Cell Stem Cell Volume 17, Issue 5, Pages 501-502 (November 2015) DOI: 10.1016/j.stem.2015.10.006 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Stroke-Induced Recruitment of Adult NSCs from the SVZ After stroke, NSCs from the adult SVZ migrate to the cortical site of injury. SVZ-derived NSCs can be isolated from the damaged cortex and expanded as self-renewing and multipotent neurospheres. In vivo, they give rise to reactive astrocytes that contribute to glial scar formation and can be converted into neurons by forced expression of the transcription factor Ascl1. Cell Stem Cell 2015 17, 501-502DOI: (10.1016/j.stem.2015.10.006) Copyright © 2015 Elsevier Inc. Terms and Conditions