Dramatic declines in implantation and pregnancy rates in patients who undergo repeated cycles of in vitro fertilization with blastocyst transfer after.

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Dramatic declines in implantation and pregnancy rates in patients who undergo repeated cycles of in vitro fertilization with blastocyst transfer after one or more failed attempts Bruce S Shapiro, M.D., Kevin S Richter, Ph.D., Dee C Harris, Said T Daneshmand, M.D. Fertility and Sterility Volume 76, Issue 3, Pages 538-542 (September 2001) DOI: 10.1016/S0015-0282(01)01979-3

Figure 1 Scatterplots with linear regression comparing numbers of oocytes retrieved (A, R2 = .42, P<.0001), percentages of oocytes fertilized (B, R2 = .12, P=.019), blastocyst formation rates per 2pn embryo (C, R2 = .05, P=.28), and total numbers of blastocysts produced (D, R2 = .22, P=.020) between first and second cycles. Shapiro. Fertil Steril 2001. Fertility and Sterility 2001 76, 538-542DOI: (10.1016/S0015-0282(01)01979-3)