Heterogeneity in Clinical, Endoscopic, and Histologic Outcome Measures and Placebo Response Rates in Clinical Trials of Eosinophilic Esophagitis: A Systematic.

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Heterogeneity in Clinical, Endoscopic, and Histologic Outcome Measures and Placebo Response Rates in Clinical Trials of Eosinophilic Esophagitis: A Systematic Review  Christopher Ma, Bram D. van Rhijn, Vipul Jairath, Tran M. Nguyen, Claire E. Parker, Seema S. Aceves, Glenn T. Furuta, Sandeep K. Gupta, David A. Katzka, Ekaterina Safroneeva, Alain M. Schoepfer, Alex Straumann, Jonathan M. Spergel, Rish K. Pai, Brian G. Feagan, Ikuo Hirano, Evan S. Dellon, Albert J. Bredenoord  Clinical Gastroenterology and Hepatology  Volume 16, Issue 11, Pages 1714-1729.e3 (November 2018) DOI: 10.1016/j.cgh.2018.06.005 Copyright © 2018 AGA Institute Terms and Conditions

Figure 1 Endpoint reporting in EoE placebo-controlled clinical trials, stratified by year of publication. Clinical Gastroenterology and Hepatology 2018 16, 1714-1729.e3DOI: (10.1016/j.cgh.2018.06.005) Copyright © 2018 AGA Institute Terms and Conditions

Figure 2 Box-and-whisker plots for histologic, endoscopic, and symptom-based placebo response and remission in EoE clinical trials. Clinical Gastroenterology and Hepatology 2018 16, 1714-1729.e3DOI: (10.1016/j.cgh.2018.06.005) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 1 PRISMA diagram. Clinical Gastroenterology and Hepatology 2018 16, 1714-1729.e3DOI: (10.1016/j.cgh.2018.06.005) Copyright © 2018 AGA Institute Terms and Conditions

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