Effects of pH Management During Selective Antegrade Cerebral Perfusion on Cerebral Microcirculation and Metabolism: Alpha-Stat Versus pH-Stat Sebastian.

Slides:

Advertisements

Similar presentations

Exploring Spinal Cord Protection by Remote Ischemic Preconditioning: An Experimental Study Johanna Herajärvi, MD, Tuomas Anttila, MB, Henna Sarja, MB,

Advertisements

The N-methyl-D -aspartate antagonist memantine has no neuroprotective effect during hypothermic circulatory arrest: A study in the chronic porcine model

Ph-stat versus alpha-stat perfusion strategy during experimental hypothermic circulatory arrest: a microdialysis study Matti Pokela, MD, Sebastian Dahlbacka,

Topical head cooling during rewarming after experimental hypothermic circulatory arrest Matti Pokela, MD, Janne Heikkinen, MS, Fausto Biancari, MD, PhD,

Leukocyte filtration to decrease the number of adherent leukocytes in the cerebral microcirculation after a period of deep hypothermic circulatory arrest

PH-Stat Versus α-Stat Acid–Base Management Strategy During Hypothermic Circulatory Arrest Combined With Embolic Brain Injury Sebastian Dahlbacka, MS,

Leukocyte filtration improves brain protection after a prolonged period of hypothermic circulatory arrest: A study in a chronic porcine model Jussi Rimpiläinen,

Leukocyte filtration improves brain protection after a prolonged period of hypothermic circulatory arrest: A study in a chronic porcine model Jussi Rimpiläinen,

Risk-Adjusted Prolonged Length of Stay as an Alternative Outcome Measure for Pediatric Congenital Cardiac Surgery Ming Liu, MS, MA, Charlotte M. Druschel,

Hancock II Bioprosthesis for Aortic Valve Replacement: The Gold Standard of Bioprosthetic Valves Durability? Tirone E. David, MD, Susan Armstrong, MS,

Anaerobic Metabolism During Cardiopulmonary Bypass: Predictive Value of Carbon Dioxide Derived Parameters Marco Ranucci, MD, Giuseppe Isgrò, MD, Federica.

Bone marrow–derived mononuclear cell transplantation improves myocardial recovery by enhancing cellular recruitment and differentiation at the infarction.

Hypertonic Saline Dextran Improves Outcome After Hypothermic Circulatory Arrest: A Study in a Surviving Porcine Model Timo Kaakinen, MD, Hanna Alaoja,

PH-Stat Versus α-Stat Acid–Base Management Strategy During Hypothermic Circulatory Arrest Combined With Embolic Brain Injury Sebastian Dahlbacka, MS,

Long-Term Consequences of Postoperative Heart Failure After Surgery for Aortic Stenosis Compared With Coronary Surgery Farkas B. Vánky, MD, PhD, Erik.

EuroSCORE Predicts Immediate and Late Outcome After Coronary Artery Bypass Surgery Fausto Biancari, MD, PhD, Olli-Pekka Kangasniemi, MS, Johannes Luukkonen,

Cold retrograde cerebral perfusion improves cerebral protection during moderate hypothermic circulatory arrest: A long-term study in a porcine model

Shangyi Ji, MD, Jianan Yang, MD, Xiaoqing Ye, MD, Xiaolei Wang, MD

Prolonged mild hypothermia after experimental hypothermic circulatory arrest in a chronic porcine model Pekka Romsi, MDa, Janne Heikkinen, MSa, Fausto.

Metabolic and Hemodynamic Effects of High-Dose Insulin Treatment in Aortic Valve and Coronary Surgery Juha K. Koskenkari, MD, Päivi K. Kaukoranta, MD,

FDA Perspective on Clinical Trial Design for Cardiovascular Devices

Simple Index to Predict Likelihood of Skilled Nursing Facility Admission After Coronary Artery Bypass Grafting Among Older Patients David C. Chang, PhD,

Surgical Resection of a Giant Coronary Aneurysm

Susanne Lison, MD, Michael Spannagl, MD, PhD, Wulf Dietrich, MD, PhD

Pleural Metastasis of Osteosarcoma

Selective Left Subclavian Ligation in Total Aortic Arch Replacement

Total Arterial Revascularization: A Superior Strategy for Diabetic Patients Who Require Coronary Surgery James Tatoulis, MD, FRACS, Rochelle Wynne, PhD,

Who Do You Say You Are? The Annals of Thoracic Surgery

Use of Amiodarone After Major Lung Resection

Topical head cooling during rewarming after experimental hypothermic circulatory arrest Matti Pokela, MD, Janne Heikkinen, MS, Fausto Biancari, MD, PhD,

Progressive Tracheal Erosion Consecutive to a Calcified Left Thyroid Lobe Anne B. Olland, MD, MS, Pierre-Emmanuel Falcoz, MD, PhD, Nicola Santelmo, MD,

Minimized Cardiopulmonary Bypass Reduces Retinal Microembolization: A Randomized Clinical Study Using Fluorescein Angiography Riikka Rimpiläinen, MD,

Leukocyte filtration to decrease the number of adherent leukocytes in the cerebral microcirculation after a period of deep hypothermic circulatory arrest

Improved Cerebral Recovery From Hypothermic Circulatory Arrest After Remote Ischemic Preconditioning Fredrik S. Yannopoulos, MB, Tuomas Mäkelä, MB, Eija.

Anomalous Origin of Left Pulmonary Artery From Left Subclavian Artery

Sternal Closure With Tie Bands: A Word of Caution

Hybrid Management of a Giant Left Main Coronary Artery Aneurysm

Neurofibromatosis of the Esophagus

Embolized Methyl Methacrylate to the Right Atrium After Kyphoplasty

Is maintained cranial hypothermia the only factor leading to improved outcome after retrograde cerebral perfusion? An experimental study with a chronic.

Editorial Board, January 2010

Sarah C. Huen, MD, Chirag R. Parikh, MD, PhD

Severe Two-Vessel Ostial Stenosis of the Main Coronary Arteries in a Patient With Transposition of the Great Arteries After an Arterial Switch Operation

Fructose-1,6-bisphosphate for improved outcome after hypothermic circulatory arrest in pigs Pekka Romsi, MDa, Timo Kaakinen, MSa, Kai Kiviluoma, MD,

Completely Thrombosed Tricuspid Pouch Mimicking a Cardiac Tumor

Postoperative Pleural Effusion in Bronchioloalveolar Cancer

Vacuum-Assisted Closure for the Treatment of Complex Chest Wounds

Deterioration of a Tricuspid Bioprosthesis Due to Adhesion of the Native Valve Herbert Gutermann, MD, Willem Flameng, MD, PhD, Paul Herijgers, MD, PhD

Limitations of Hospital Volume as a Measure of Quality of Care for Coronary Artery Bypass Graft Surgery Karl F. Welke, MD, Mitchell J. Barnett, PharmD,

Anirudh Vinnakota, MS, Robert Stewart, MD, Gosta Pettersson, MD, PhD

Jorge D. Salazar, MD, Ryan D

Patrick O. Myers, MD The Annals of Thoracic Surgery

Specialty Training and Mortality After Esophageal Cancer Resection

Massimo Meco, MD, Silvia Cirri, MD The Annals of Thoracic Surgery

Dana Y. Fuhrman, DO, MS, Lan G

Invited Commentary The Annals of Thoracic Surgery

Robert Lee Replogle, September 30, 1931–May 9, 2016

Randomized Controlled Trial of Pericardial Blood Processing With a Cell-Saving Device on Neurologic Markers in Elderly Patients Undergoing Coronary Artery.

“Transitions” for Cardiothoracic Surgeons Now Listed on the Web:

Posttraumatic Main Left Bronchial Rupture

Increased Rehospitalization Rate After Coronary Bypass Operation for Acute Coronary Syndrome: A Prospective Study in 200 Patients Staffan Bjessmo, MD,

Perfusing the Cold Brain: Optimal Neuroprotection for Aortic Surgery

Experience With Bovine Pericardium for the Reconstruction of the Aortic Arch in Patients Undergoing a Norwood Procedure Victor O. Morell, MD, Peter A.

Late Consequences of a Much Earlier Decision

Heather M. Phelps, DO, William T

The Impact of New Technology on Cardiothoracic Surgical Practice

Slide Tracheoplasty in Infants and Children: Risk Factors for Prolonged Postoperative Ventilatory Support Peter B. Manning, MD, Michael J. Rutter, MD,

Domenico Galetta, MD, PhD, Lorenzo Spaggiari, MD, PhD

Surgical Reconstruction of Peripheral Pulmonary Arteries: Strategies, Outcomes, and New Classification Abdulaziz Al-Khaldi, MD, MS, Omar Tamimi, MD

Harvey Edward Garrett, MD, Bradley A. Wolf, MD

Presentation transcript:

Effects of pH Management During Selective Antegrade Cerebral Perfusion on Cerebral Microcirculation and Metabolism: Alpha-Stat Versus pH-Stat Sebastian Dahlbacka, MD, Hanna Alaoja, MS, Jussi Mäkelä, MS, Eija Niemelä, MS, Päivi Laurila, MD, PhD, Kai Kiviluoma, MD, PhD, Anna Honkanen, MS, Pasi Ohtonen, MS, Vesa Anttila, MD, PhD, Tatu Juvonen, MD, PhD The Annals of Thoracic Surgery Volume 84, Issue 3, Pages 847-855 (September 2007) DOI: 10.1016/j.athoracsur.2007.03.065 Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Brain arterial diameters (left), adherent leukocytes (center), and tissue oxygenation (right) in pigs undergoing selective cerebral perfusion (SCP) and being monitored using either α-stat (solid squares; n = 10) or pH-stat (open circles; n = 10) strategy. (m = minutes; NADH = reduced nicotinamide adenine dinucleotide.) The Annals of Thoracic Surgery 2007 84, 847-855DOI: (10.1016/j.athoracsur.2007.03.065) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Key brain microdialysis findings for brain lactate concentration (left), brain lactate to pyruvate ratio (center), and brain glycerol concentration (right) in pigs undergoing selective cerebral perfusion (SCP) and being monitored with either α-stat (solid squares; n = 12) or pH-stat (open circles; n = 12) strategy. (postop = postoperative.) The Annals of Thoracic Surgery 2007 84, 847-855DOI: (10.1016/j.athoracsur.2007.03.065) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions