Imaging in Liver Malignancy

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Presentation transcript:

Imaging in Liver Malignancy

Program Objectives

Clinical Impact of Focal Liver Lesions

HCC

Contemporary Imaging Approaches

Ultrasound

Ultrasound Limitations

Ultrasound Liver Imaging Reporting and Data System

Ultrasound Limited Sensitivity Compared to CECT/MRI

Contrast-Enhanced Ultrasound

Multi-Detector CT

Multi-Detector CT

Multiple Phases

Injection Rate

Cumulative Radiation Dose

Radiation Dose

Standard Radiation Dose CT Vs Reduced Dose CT

Dual Energy CT

Low keV

Iodine Quantification for Characterization of Indeterminate Liver Lesions

Virtual Non-Contrast CT

Value of Non-Contrast CT

MRI and Advantages Over CT

Multiphasic Arterial Phase (I)

Multiphasic Arterial Phase (II)

MRI and Advantages Over CT

Increased Contrast Enhancement at MRI

Increased Detection of Capsule and Washout

MRI and Advantages Over CT

MRI: Fat

MRI: Fat Increased Lesion Characterization

MRI: Fat (II)

MRI and Advantages Over CT

HBP Agents Gadoxetate

HBP Agents Vascular + Function

HBP for Lesion Characterization Adenoma

Progression to HCC (I)

Progressed HCC

Early HCC

HCC Grading

Microvascular Tumor Invasion

HBP for Metastatic Disease (I)

HBP for Metastatic Disease (III)

Limitations of MRI

Different Sequences Acquired in Conventional MRI Examination

Abbreviated MRI Protocol for HCC Surveillance

Abbreviated MRI Protocol (~ 15 Minutes)

Conclusions

Abbreviations

Abbreviations (cont)