Reduced-Intensity Allografting as First Transplantation Approach in Relapsed/Refractory Grades One and Two Follicular Lymphoma Provides Improved Outcomes.

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Presentation transcript:

Reduced-Intensity Allografting as First Transplantation Approach in Relapsed/Refractory Grades One and Two Follicular Lymphoma Provides Improved Outcomes in Long-Term Survivors  Evgeny Klyuchnikov, Ulrike Bacher, Nicolaus M. Kröger, Parameswaran N. Hari, Kwang Woo Ahn, Jeanette Carreras, Veronika Bachanova, Asad Bashey, Jonathon B. Cohen, Anita D'Souza, César O. Freytes, Robert Peter Gale, Siddhartha Ganguly, Mark S. Hertzberg, Leona A. Holmberg, Mohamed A. Kharfan-Dabaja, Andreas Klein, Grace H. Ku, Ginna G. Laport, Hillard M. Lazarus, Alan M. Miller, Alberto Mussetti, Richard F. Olsson, Shimon Slavin, Saad Z. Usmani, Ravi Vij, William A. Wood, David G. Maloney, Anna M. Sureda, Sonali M. Smith, Mehdi Hamadani  Biology of Blood and Marrow Transplantation  Volume 21, Issue 12, Pages 2091-2099 (December 2015) DOI: 10.1016/j.bbmt.2015.07.028 Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Survival outcomes for all patients (n = 518). (A) Adjusted probabilities for NRM (5 years; P < .001). (B) Adjusted probabilities for relapse (5 years; P < .001). (C) Adjusted probabilities for PFS (5 years; P < .001). (D) Adjusted probabilities for OS (5 years; P = .05). Biology of Blood and Marrow Transplantation 2015 21, 2091-2099DOI: (10.1016/j.bbmt.2015.07.028) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Landmark analysis in long-term survivors (≥24 months). (A) PFS (P < .0001). (B) OS (P = .0063). Biology of Blood and Marrow Transplantation 2015 21, 2091-2099DOI: (10.1016/j.bbmt.2015.07.028) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions