A Novel and Reliable Method to Detect Microsatellite Instability in Colorectal Cancer by Next-Generation Sequencing Lizhen Zhu, Yanqin Huang, Xuefeng.

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A Novel and Reliable Method to Detect Microsatellite Instability in Colorectal Cancer by Next-Generation Sequencing Lizhen Zhu, Yanqin Huang, Xuefeng Fang, Chenglin Liu, Wanglong Deng, Chenhan Zhong, Jinghong Xu, Dong Xu, Ying Yuan The Journal of Molecular Diagnostics Volume 20, Issue 2, Pages 225-231 (March 2018) DOI: 10.1016/j.jmoldx.2017.11.007 Copyright © 2018 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

Figure 1 The percentages of length-instability loci in MSS and MSI-H samples for the ColonCore panel, MSIsensor, and mSINGS. Each dot represents one sample. The percentages are more readily distinguished in the ColonCore panel versus those from MSIsensor and mSINGS. The Journal of Molecular Diagnostics 2018 20, 225-231DOI: (10.1016/j.jmoldx.2017.11.007) Copyright © 2018 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

Figure 2 Mutation burden of MSS and MSI-H samples reported by the PCR method. Each dot represents one sample. The mutation burden is not highly distinguishable between these two types of samples. The Journal of Molecular Diagnostics 2018 20, 225-231DOI: (10.1016/j.jmoldx.2017.11.007) Copyright © 2018 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions