Basic Patterns of Human Inheritance

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Presentation transcript:

Basic Patterns of Human Inheritance Chapter 11 Section 1

Main Idea The inheritance of a trait over several generations can be shown in a pedigree.

What are examples of dominant and recessive disorders? Thinking Questions How can genetic patterns be analyzed to determine dominant or recessive inheritance patterns? What are examples of dominant and recessive disorders? How can human pedigrees be constructed from genetic information? Copyright © McGraw-Hill Education

Recessive Genetic Disorders A recessive trait is expressed when the individual is homozygous recessive for the trait. Those with at least one dominant allele will not express the recessive disorder. An individuals who is heterozygous for a recessive disorder is called a carrier.

Cystic fibrosis Recessive Genetic Disorders A disorder that affects the mucous- producing glands, digestive enzymes, and sweat glands. Cystic fibrosis causes mucus excretion that clogs ducts in the pancreas, interrupts digestion, and blocks respiratory pathways in the lungs. Average life expectancy: 37 years

Albinism Recessive Genetic Disorders Albinism is caused by altered genes, resulting in the absence of the skin pigment melanin in hair and eyes. Individuals with albinism have very pale skin, white hair, and pink irises. Not considered fatal, but can lead to other problems – skin cancer and vision problems

Tay-Sachs disease Recessive Genetic Disorders Caused by the absence of DNA instructions that code for the production of an enzyme responsible for breaking down fats in cells. Fats accumulate in brain cells, inflating brain nerve cells and causing mental deterioration. Average life expectancy: 3 years

Galactosemia Recessive Genetic Disorders Recessive genetic disorder characterized by the inability of the body to digest galactose. Inability to digest milk products Not to be confused with lactose intolerance If a strict diet is followed, individuals can lead a normal life If not, death can occur quickly

Dominant Genetic Disorders Some disorders are caused by dominant alleles. That means that the only way to not have the disease is to be homozygous recessive Only ONE COPY of the dominant allele is necessary

Huntington’s disease Achondroplasia Dominant Genetic Disorders Affects the nervous system, causing gradual loss of brain function Occurs in 1 out of every 10,000 people in the US Achondroplasia Causes small body size and limbs that are comparatively short Caused by an abnormal gene that affects bone growth

Pedigrees A pedigree is a diagram that traces the inheritance of a particular trait through several generations.

Analyzing Pedigrees Pedigrees can be used to examine both recessive and dominant genetic disorders. Information about an individual’s genotype can be inferred from the phenotype of his/her parents and offspring. Dominant disorder Recessive disorder

Inferring Genotypes Predicting Disorders Analyzing Pedigrees Knowing physical traits can determine what genes an individual is most likely to have. Predicting Disorders Record keeping helps scientists use pedigree analysis to study inheritance patterns, determine phenotypes, and ascertain genotypes.

Merry Christmas, Happy Holidays!!

What are examples of dominant and recessive disorders? Thinking Questions How can genetic patterns be analyzed to determine dominant or recessive inheritance patterns? What are examples of dominant and recessive disorders? How can human pedigrees be constructed from genetic information? Copyright © McGraw-Hill Education