Oral phenylephrine: An ineffective replacement for pseudoephedrine?

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Presentation transcript:

Oral phenylephrine: An ineffective replacement for pseudoephedrine? Leslie Hendeles, PharmD, Randy C. Hatton, PharmD Journal of Allergy and Clinical Immunology Volume 118, Issue 1, Pages 279-280 (July 2006) DOI: 10.1016/j.jaci.2006.03.002 Copyright © 2006 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 1 Percent change in nasal airway resistance in 20 patients with chronic nasal stuffiness after single doses of placebo and 3 oral decongestants administered in a randomized, double-blind, crossover manner on different days. Changes were significant at each time point after pseudoephrine and phenylpropanolamine but not after phenylephrine. Drawn from data presented by Bickerman.5 This graph was previously published11 and is reproduced with permission of Pharmacotherapy. Journal of Allergy and Clinical Immunology 2006 118, 279-280DOI: (10.1016/j.jaci.2006.03.002) Copyright © 2006 American Academy of Allergy, Asthma and Immunology Terms and Conditions