Idiopathic Pulmonary Hemorrhage Christian G. Brambilla, M.D., Elizabeth M. Brambilla, M.D., Pierre Stoebner, M.D., Elizabeth Dechelette, M.D.  CHEST  Volume 81, Issue 1, Pages 120-123 (January 1982) DOI: 10.1378/chest.81.1.120 Copyright © 1982 The American College of Chest Physicians Terms and Conditions

Figure 1 Alveolar septa. Capillaries, junctions and basement membranes are normal, even at right, where deposits of iron and calcium are present between capillary and alveolar basement membrane. CHEST 1982 81, 120-123DOI: (10.1378/chest.81.1.120) Copyright © 1982 The American College of Chest Physicians Terms and Conditions

Figure 2 Deposits of iron and calcium on alveolar basement membrane. Amount of calcium is lower than iron. CHEST 1982 81, 120-123DOI: (10.1378/chest.81.1.120) Copyright © 1982 The American College of Chest Physicians Terms and Conditions

Figure 3 Deposits are numerous on basement membrane facing alveolar lumen and seldom are found on deeper interstitial side of capillaries. CHEST 1982 81, 120-123DOI: (10.1378/chest.81.1.120) Copyright © 1982 The American College of Chest Physicians Terms and Conditions

Figure 4 Alveolar macrophage. Inclusions of hemosiderin contain iron but no calcium. Lower left, Macrophage is observed on transmission electron microscope. Upper right, Thin section of macrophage is observed on scanning electron microscope. Shadow of cell is visible, and inclusions of hemosiderin have higher secondary electron emission than cell's cytoplasm. Upper left, Mapping of iron of same cell is shown by x-ray microanalysis. CHEST 1982 81, 120-123DOI: (10.1378/chest.81.1.120) Copyright © 1982 The American College of Chest Physicians Terms and Conditions