Disjunction of the polarity of the Golgi apparatus and the nuclear dense lamina (NDL) in Spink2−/− round spermatids and presence of multivesicular bodies.

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Disjunction of the polarity of the Golgi apparatus and the nuclear dense lamina (NDL) in Spink2−/− round spermatids and presence of multivesicular bodies in the cytoplasm of Spink2−/− round spermatids Disjunction of the polarity of the Golgi apparatus and the nuclear dense lamina (NDL) in Spink2−/− round spermatids and presence of multivesicular bodies in the cytoplasm of Spink2−/− round spermatids Partial section of a Spink2−/− round spermatid observed by EM showing the spatial disjunction of the Golgi apparatus and the NDL. NDL is evidenced by apposition of dense material on the nuclear side of the inner nuclear membrane. Another hallmark of this specialized area of the nuclear envelope is the tight apposition of both inner and outer nuclear membranes along the NDL. M, mitochondria. Scale bar, 2 μm.Partial section of a Spink2−/− round spermatid observed by EM showing structures corresponding to multivesicular bodies (MVB). M, mitochondria; NE, nuclear envelope; NDL, nuclear dense lamina. Scale bar, 2 μm. Zine‐Eddine Kherraf et al. EMBO Mol Med. 2017;emmm.201607461 © as stated in the article, figure or figure legend