Effect of Different Sympathetic Stimuli–Autonomic Dysreflexia and Head-up Tilt–on Leg Vascular Resistance in Spinal Cord Injury Jan T. Groothuis, MD,

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Effect of Different Sympathetic Stimuli–Autonomic Dysreflexia and Head-up Tilt–on Leg Vascular Resistance in Spinal Cord Injury Jan T. Groothuis, MD, Gerard A. Rongen, MD, PhD, Alexander C. Geurts, MD, PhD, Paul Smits, MD, PhD, Maria T. Hopman, MD, PhD Archives of Physical Medicine and Rehabilitation Volume 91, Issue 12, Pages 1930-1935 (December 2010) DOI: 10.1016/j.apmr.2010.09.004 Copyright © 2010 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 1 Leg vascular resistance in persons with SCI (n=9) and controls (n=9) during exaggerated sympathetic activity, autonomic dysreflexia in persons with SCI or CPT in controls, and 30° HUT. Values represent mean + SE. Abbreviations: AD, autonomic dysreflexia; AU, arbitrary units. *Significantly different from baseline. Archives of Physical Medicine and Rehabilitation 2010 91, 1930-1935DOI: (10.1016/j.apmr.2010.09.004) Copyright © 2010 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 2 MAP in persons with SCI (n=9) and controls (n=9) during exaggerated sympathetic activity, autonomic dysreflexia in persons with SCI or CPT in controls, and 30° HUT. Values represent mean + SE. Abbreviation: AD, autonomic dysreflexia. *Significantly different from baseline. Archives of Physical Medicine and Rehabilitation 2010 91, 1930-1935DOI: (10.1016/j.apmr.2010.09.004) Copyright © 2010 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 3 Schematic representation of the vasoconstriction reserve in control subjects and persons with SCI. Leg vascular resistance in supine (Supine) position during CPT, HUT, HUT combined with CPT (HUT+CPT), and autonomic dysreflexia (AD) are indicated. Whether maximal vasoconstriction is established during HUT combined with CPT in control subjects and HUT or AD in persons with SCI is not known. Archives of Physical Medicine and Rehabilitation 2010 91, 1930-1935DOI: (10.1016/j.apmr.2010.09.004) Copyright © 2010 American Congress of Rehabilitation Medicine Terms and Conditions