P Bodies and the Control of mRNA Translation and Degradation

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P Bodies and the Control of mRNA Translation and Degradation Roy Parker, Ujwal Sheth Molecular Cell Volume 25, Issue 5, Pages 635-646 (March 2007) DOI: 10.1016/j.molcel.2007.02.011 Copyright © 2007 Elsevier Inc. Terms and Conditions

Figure 1 The General Pathways and Nuclease Complexes for Degradation of Eukaryotic mRNAs Molecular Cell 2007 25, 635-646DOI: (10.1016/j.molcel.2007.02.011) Copyright © 2007 Elsevier Inc. Terms and Conditions

Figure 2 The mRNA Cycle: A Model for the Cycling of Eukaryotic mRNAs between Different Subcellular Compartments Molecular Cell 2007 25, 635-646DOI: (10.1016/j.molcel.2007.02.011) Copyright © 2007 Elsevier Inc. Terms and Conditions

Figure 3 Function of mRNAs May Reflect Competition between Assembly of Translation Initiation Complexes and Translation Repression Complexes Molecular Cell 2007 25, 635-646DOI: (10.1016/j.molcel.2007.02.011) Copyright © 2007 Elsevier Inc. Terms and Conditions

Figure 4 mRNA-Specific Recruitment of the General Repression and Decay Complexes Examples of how mRNA-specific regulators may recruit the general repression and decay complexes to individual transcripts, thereby promoting deadenylation, translation repression, accumulation in P bodies, and decapping. Molecular Cell 2007 25, 635-646DOI: (10.1016/j.molcel.2007.02.011) Copyright © 2007 Elsevier Inc. Terms and Conditions