Activity-Based Profiling of 2-Oxoglutarate Oxygenases

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Presentation transcript:

Activity-Based Profiling of 2-Oxoglutarate Oxygenases Paul P. Geurink, Bogdan I. Florea, Herman S. Overkleeft  Chemistry & Biology  Volume 18, Issue 5, Pages 557-559 (May 2011) DOI: 10.1016/j.chembiol.2011.05.002 Copyright © 2011 Elsevier Ltd Terms and Conditions

Figure 1 Rational Design of Activity-Based 2-OG Probes (A) General mechanism of 2-oxoglutarate-dependent oxygenases. (B) Activity-based 2-OG probes employed in the highlighted studies. (C) General flowscheme of activity-based 2-OG profiling. Chemistry & Biology 2011 18, 557-559DOI: (10.1016/j.chembiol.2011.05.002) Copyright © 2011 Elsevier Ltd Terms and Conditions

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