Of Brains and Blood: Developmental Origins of Glioma Diversity?

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Of Brains and Blood: Developmental Origins of Glioma Diversity? Mariella G. Filbin, Charles D. Stiles Cancer Cell Volume 28, Issue 4, Pages 403-404 (October 2015) DOI: 10.1016/j.ccell.2015.09.013 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Glioblastoma Diversity Arising from Differentially Restricted Progenitor Cells Schematic of sagittal mouse brain slice showing that two different glioblastoma subtypes (type 1 gliomas and type 2 gliomas) can be generated by stem cells or differentially restricted progenitor cells with identical driver mutations. NSC, neural stem cell; NPC, neural progenitor cell; OPC, oligodendrocyte progenitor cell; SVZ, subventricular zone; SGZ, subgranular zone. Cancer Cell 2015 28, 403-404DOI: (10.1016/j.ccell.2015.09.013) Copyright © 2015 Elsevier Inc. Terms and Conditions