Volume 4, Issue 8, Pages (September 2018)

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Volume 4, Issue 8, Pages 761-765 (September 2018) Nivolumab-induced alopecia areata: A reversible factor of good prognosis? Myriam Lakhmiri, MD, Bénédicte Cavelier-Balloy, MD, Caroline Lacoste, MD, Charles Cassius, MD, MSc, Barouyr Baroudjian, MD, Julie Delyon, MD, MSc, Céleste Lebbé, MD, PhD, Pascal Reygagne, MD JAAD Case Reports Volume 4, Issue 8, Pages 761-765 (September 2018) DOI: 10.1016/j.jdcr.2018.05.022 Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Nivolumab-induced AA before treatment in metastatic lung cancer (case 1). JAAD Case Reports 2018 4, 761-765DOI: (10.1016/j.jdcr.2018.05.022) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Dermoscopy shows yellow and black dots and anisotrichia in nivolumab-induced AA used for metastatic lung cancer (case 1). JAAD Case Reports 2018 4, 761-765DOI: (10.1016/j.jdcr.2018.05.022) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 A, Nivolumab-induced AA before treatment in metastatic lung cancer (case 2). B, Nivolumab-induced AA regrowth after 3 months of treatment (case 2). JAAD Case Reports 2018 4, 761-765DOI: (10.1016/j.jdcr.2018.05.022) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 4 Dermoscopy shows yellow and black dots, anisotrichia, and poliosis in nivolumab-induced AA before treatment in lung cancer (case 2). JAAD Case Reports 2018 4, 761-765DOI: (10.1016/j.jdcr.2018.05.022) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 5 Histology shows perifollicular lymphocytic infiltrate and a follicular miniaturization in nivolumab-induced AA used for metastatic lung cancer (case 2). JAAD Case Reports 2018 4, 761-765DOI: (10.1016/j.jdcr.2018.05.022) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 6 A, Nivolumab-induced AA before treatment in metastatic melanoma (case 3). B, Nivolumab-induced AA regrowth after 9 months of treatment (case 3). JAAD Case Reports 2018 4, 761-765DOI: (10.1016/j.jdcr.2018.05.022) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 7 Dermoscopy shows yellow and black dots, anisotrichia, and poliosis in nivolumab-induced AA after treatment in metastatic melanoma (case 3). JAAD Case Reports 2018 4, 761-765DOI: (10.1016/j.jdcr.2018.05.022) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 8 Histology shows a miniaturization of hair with telogen follicles with a slight perifollicular lymphocytic infiltrate in nivolumab-induced AA used for metastatic melanoma (case 3). JAAD Case Reports 2018 4, 761-765DOI: (10.1016/j.jdcr.2018.05.022) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 9 A and B, Nivolumab-induced AA before treatment in metastatic melanoma. Clinical photographs show a typical patch of AA (case 4). JAAD Case Reports 2018 4, 761-765DOI: (10.1016/j.jdcr.2018.05.022) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions