α-Synuclein and Tau: Mitochondrial Kill Switches

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α-Synuclein and Tau: Mitochondrial Kill Switches Ulrike Pech, Patrik Verstreken Neuron Volume 97, Issue 1, Pages 3-4 (January 2018) DOI: 10.1016/j.neuron.2017.12.024 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Model of the Defects Proposed to be Common to α-syn and Tau Models Both phosphorylated α-syn and Tau impair cytoskeleton dynamics, in turn leading to disrupted Drp1-mediated mitochondrial fission and defects in mitochondrial integrity. Neuron 2018 97, 3-4DOI: (10.1016/j.neuron.2017.12.024) Copyright © 2017 Elsevier Inc. Terms and Conditions