Immunization Update 2007 Varicella Vaccine Segment Satellite Broadcast/Webcast August 9, 2007 Varicella Vaccine Segment Graphics subject to change. This material in the public domain.

Varicella in the United States Coverage with one dose at highest level ever recorded (88%) More than 70% decrease in cases, hospitalizations and death compared to prevaccine era

Varicella Outbreaks 2001-2005 Occurred in elementary schools Vaccine effectiveness 72%-85% Highest attack rates occurred among the younger students Outbreaks lasted about 2 months Vaccinated children played a role in transmission although their disease was mild Overall attack rates among vaccinated children 11%-17%

Varicella Vaccine Recommendations Routine vaccination at 12 to 15 months of age Routine second dose at 4 to 6 years of age Two doses recommended for all persons older than 4 to 6 years who do not have evidence of varicella immunity Second dose recommended for persons of ANY age who have only received one dose Source: MMWR 2007;56(RR-4)

Varicella Vaccine-Minimum Interval Between Doses 3 months 4 weeks Age 12 months through 12 years of age 13 years of age or older Source: MMWR 2007;56(RR-4)

Varicella Immunity Written documentation of age-appropriate vaccination 1 dose for preschool-aged children 2 doses for school-aged children, adolescents and adults Born in the United States before 1980 EXCEPT healthcare personnel, immunocompromised persons and pregnant women Source: MMWR 2007;56(RR-4)

Varicella Immunity Laboratory evidence of immunity or laboratory confirmation of varicella disease Healthcare provider diagnosis or verification of a history of varicella disease History of herpes zoster (shingles) based on healthcare provider diagnosis Source: MMWR 2007;56(RR-4)

Varicella Vaccination of Healthcare Workers Recommended for all healthcare personnel without evidence of immunity Prevaccination serologic screening probably cost-effective Postvaccination testing not necessary or recommended Source: MMWR 1997;46(RR-18)

Varicella Immunity Among Healthcare Personnel Laboratory evidence of immunity History of clinician diagnosed or verified varicella or zoster Documentation of age-appropriate vaccination Source: MMWR 2007;56(RR-4)

MMRV (ProQuad) Approved for children 12 months through 12 years of age Should NOT be administered to persons 13 years of age or older Store frozen at 5°F (-15°C ) or lower at ALL times

Website www.cdc.gov/nip CDC Vaccines and Immunization Contact Information Hotline (800) CDC-INFO Email nipinfo@cdc.gov Website www.cdc.gov/nip Broadcast Updates and Resources Web Page www.cdc.gov/vaccines/ed/broadcasts.htm