Volume 113, Issue 5, Pages (May 2003)

Slides:

Advertisements

Similar presentations

A Role for Dystroglycan in Basement Membrane Assembly Michael D Henry, Kevin P Campbell Cell Volume 95, Issue 6, Pages (December 1998) DOI: /S (00)

Advertisements

Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding J. Winter, M. Ilbert, P.C.F. Graf, D. Özcelik, U. Jakob Cell Volume 135, Issue.

Lessons from Hereditary Colorectal Cancer

Determination of the Interfacial Water Content in Protein-Protein Complexes from Free Energy Simulations Peter Monecke, Thorsten Borosch, Jürgen Brickmann,

The Nuclear Pore Complex Mystery and Anomalous Diffusion in Reversible Gels Thomas Bickel, Robijn Bruinsma Biophysical Journal Volume 83, Issue 6, Pages.

A Two-Step Scaffolding Model for Mitotic Chromosome Assembly Kazuhiro Maeshima, Ulrich K. Laemmli Developmental Cell Volume 4, Issue 4, Pages (April.

Cell Traction Forces Direct Fibronectin Matrix Assembly Christopher A. Lemmon, Christopher S. Chen, Lewis H. Romer Biophysical Journal Volume 96, Issue.

Susanne Wingert, Michael A. Rieger Experimental Hematology

Invariant Chain Structure and MHC Class II Function

Genome Organization: Cohesin on the Move

Charles Swanton, Julian Downward Cancer Cell

RNA-Directed DNA Methylation: Getting a Grip on Mechanism

Protein secretion: Getting folded proteins across membranes

Molecular chaperones: Pathways and networks

Something Old, Something New, Something Borrowed …

Electrostatic Fasteners Hold the T Cell Receptor-CD3 Complex Together

Volume 89, Issue 4, Pages (May 1997)

Cyclin C Makes an Entry into the Cell Cycle

162. Stability of Polymer/Plasmid DNA Complexes In Vitro and In Vivo

Heat shock protein 90 as a molecular target for cancer therapeutics

DNA Polymerase III: Running Rings around the Fork

Chaperones. CA García Sepúlveda MD PhD

Volume 104, Issue 6, Pages (March 2001)

TFIIS and GreB Cell Volume 114, Issue 3, Pages (August 2003)

Twin Ushers Guide Pili across the Bacterial Outer Membrane

Nuclear Export Receptors: From Importin to Exportin

Rad53 Cell Volume 115, Issue 5, Pages (November 2003)

Identification of TOR Signaling Complexes

Guiding Endosomal Maturation

Actin and Apical Constriction: Some (Re)-Assembly Required

Peroxisomal Protein Import

Eukaryotic Transcription Activation: Right on Target

P.M. Keig, E. Ingham, P.A.R. Vandamme, K.G. Kerr

Cellular Handling of Protein Aggregates by Disaggregation Machines

Rheumatoid Arthritis Cell Volume 85, Issue 3, Pages (May 1996)

Roger Schneiter, Sepp D Kohlwein Cell

Volume 9, Issue 6, Pages (June 2002)

Susanne Wingert, Michael A. Rieger Experimental Hematology

The Pyrenoid: An Overlooked Organelle Comes out of Age

Transfer of Cholesterol by the NPC Team

Volume 23, Issue 7, Pages R273-R276 (April 2013)

MCM Loading—An Open-and-Shut Case?

Genetics of E. coli fimbriae.

The Ubiquitin Proteasome System in Neurodegenerative Diseases

Transforming CO2 by Stabilizing the Labile Product

Breaking Down Order to Keep Cells Tidy

Molecular Structure of the PKD Protein Complex Finally Solved

A New Trigger for T Cells

Volume 9, Issue 11, Pages (November 2001)

F1-ATPase: A Rotary Motor Made of a Single Molecule

Volume 92, Issue 3, Pages (February 1998)

Genome Organization: Cohesin on the Move

Tuning Bulk Electrostatics to Regulate Protein Function

Establishment of Sister Chromatid Cohesion

Table of contents The Journal for Nurse Practitioners

Coordination of Two Genomes by Mitochondrial Translational Plasticity

Structure of BamHI Bound to Nonspecific DNA

The Ballet of Morphogenesis

Charles A. Herzog Kidney International

Volume 70, Issue 3, Pages (August 2006)

How to Assemble a Capsid

Intracellular Transport: How Do Motors Work Together?

A New Cohesive Team to Mediate DNA Looping

Molecular Recognition of Cargo by the COPII Complex

Lysosomal Rag-ulation of mTOR Complex 1 Activity

There's a Time and a Place for MYCN

PP2A fulfills its promises as tumor suppressor

TFIIS and GreB Cell Volume 114, Issue 3, Pages (August 2003)

Volume 113, Issue 5, Pages (May 2003)

Asf1, a Loveseat for a Histone Couple

Presentation transcript:

Volume 113, Issue 5, Pages 556-557 (May 2003) Periplasmic Chaperones—Preservers of Subunit Folding Energy for Organelle Assembly Susanne Behrens Cell Volume 113, Issue 5, Pages 556-557 (May 2003) DOI: 10.1016/S0092-8674(03)00396-9

Figure 1 Simplified Model of Chaperone-Mediated Fiber Assembly Driven by Folding Energy The chaperone arrests subunit folding and traps it in a high-energy folding state. At the usher pore, an incoming chaperone-subunit complex (C2:S4*) displaces the chaperone from the terminal fiber subunit (C1:S3*) by DSE, allowing this subunit to repack into the final conformation (S3). The free energy of this collapse is thought to drive the assembly process. C, chaperone; S, subunit. The asterisk indicates the high-energy folding state of chaperone-bound subunits. Cell 2003 113, 556-557DOI: (10.1016/S0092-8674(03)00396-9)