Amide bonds in a polypeptide

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Presentation transcript:

Amide bonds in a polypeptide Amide bonds in a polypeptide In this figure, the symbol R is used to denote the different functional groups that distinguish the amino acids. The amino acids that polymerize to form a polypeptide or protein are joined together through amide bonds. This bond is often referred to as a peptide bond. The carbon, oxygen and nitrogen atoms of the amide group all lie in the same plane with the lone pair on the nitrogen forming a delocalized system with the electrons from the carbon–oxygen double bond, as was described for the carboxylate anion. The planarity of this bond has important implications for protein structure. Amanda L. Jonsson et al. Essays Biochem. 2017;61:401-427 ©2017 by Portland Press Ltd