2nd International Summit on Human Genome Editing Hong Kong

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Presentation transcript:

2nd International Summit on Human Genome Editing Hong Kong November 27, 2018 Dana Carroll Department of Biochemistry University of Utah School of Medicine

Asilomar, 1975 First Summit on Human Gene Editing, 2015

What CRISPR does – genome editing Gene KO CRISPR Cell activities Gene correction

Human embryo injection Dr. Kathy Niakan, Nature Published in Science 09.20.2017

CRISPR’s unintended consequences Gene KO CRISPR Cell activities Gene correction Off-target mutations

Distribution of the sickle allele University of Oxford US FDA