Finding the Right Option: Hormone Receptor-Positive Advanced Breast Cancer
Hormone Receptor-Positive Advanced Breast Cancer Introduction
Case Study 1
Case Study 1 (cont)
Response to Therapy
ASCO Key Guideline Recommendations for Hormone Receptor-Positive MBC
ASCO Key Guideline Recommendations for Hormone Receptor-Positive MBC (cont)
Endocrine Trials in First-Line MBC
Emerging Therapies for Hormone Receptor-Positive Breast Cancer
FALCON Anastrozole vs Fulvestrant in Hormone Receptor-Positive Advanced or MBC
FALCON Results
PALOMA-1 Palbociclib Plus Letrozole vs Letrozole Alone
PALOMA-1 Results
PALOMA-2 Palbociclib Plus Letrozole vs Letrozole Alone
PALOMA-2 Results
PALOMA-2 AE Summary
MONALEESA-2 Ribociclib Plus Letrozole vs Letrozole in Hormone Receptor-Positive Advanced Breast Cancer
MONALEESA-2 Results
MONALEESA-2 Safety Profile
Case Study 2
Case Study 2 (cont)
Options for Patients Who Have Disease Progression During/After Endocrine Therapy
PALOMA-3 Fulvestrant ± Palbociclib
PALOMA-3 Results
ESR1 Mutations
ESR1 Mutations Results
MONARCH 1 Abemaciclib
MONARCH1 Results
neoMONARCH Neoadjuvant Phase 2 Trial Interim Analysis
neoMONARCH Ki67 Results
Neoadjuvant Palbociclib With Anaztrozole
BOLERO-2 Everolimus Plus Exemestane vs Placebo Plus Exemestane
BOLERO-2 Results
SWISH Trial: Dexamethasone-Based Mouthwash for Stomatitis
Emerging Strategies
Conclusions
Abbreviations
Abbreviations (cont)
Abbreviations (cont)