Evaluation of a New Ultrasound Thoracoscope for Localization of Lung Nodules in Ex Vivo Human Lungs Hideki Ujiie, MD, PhD, Tatsuya Kato, MD, PhD, Hsin-pei.

Slides:

Advertisements

Similar presentations

A Rare Case of Solitary Plasmacytoma Mimicking a Primary Lung Tumor

Advertisements

Evaluation of a New Ultrasound Thoracoscope for Localization of Lung Nodules in Ex Vivo Human Lungs Hideki Ujiie, MD, PhD, Tatsuya Kato, MD, PhD, Hsin-pei.

Marcelo Cypel, MD, MSc, Jonathan C

Robot-Assisted Thoracoscopic Lobectomy for Early-Stage Lung Cancer

Endoscopic Ultrasound-Guided Fine Needle Aspiration of Mediastinal Lymph Node in Patients With Suspected Lung Cancer After Positron Emission Tomography.

Pulmonary Lobectomy in a Patient With a Left Ventricular Assist Device

Left Video-Assisted Thoracoscopic Surgery Esophagectomy in a Patient With Situs Inversus Totalis and Kartagener Syndrome John Peel, BHSc, Gail Darling,

Near-Infrared Intraoperative Molecular Imaging Can Locate Metastases to the Lung Jane Keating, MD, Andrew Newton, MD, Ollin Venegas, BA, Sarah Nims, BS,

Ex Vivo Four-Dimensional Lung Cancer Model Mimics Metastasis

A Proposal for Definition of Minimally Invasive Adenocarcinoma of the Lung Regardless of Tumor Size Shigeki Suzuki, MD, Hiroyuki Sakurai, MD, Kyohei.

Chest Wall Angiolipoma Complicating Von Recklinghausen Disease

Radiologic Characteristics of Surgically Resected Non-Small Cell Lung Cancer With ALK Rearrangement or EGFR Mutations Tae Jung Kim, MD, PhD, Choon-Taek.

Impact of Solid Minor Histologic Subtype in Postsurgical Prognosis of Stage I Lung Adenocarcinoma Tianxiang Chen, MD, PhD, Jizhuang Luo, MD, Haiyong.

A prospective controlled trial of endobronchial ultrasound-guided transbronchial needle aspiration compared with mediastinoscopy for mediastinal lymph.

Real-Time Computed Tomography Highlights Pulmonary Parenchymal Evolution During Ex Vivo Lung Reconditioning Edouard Sage, MD, PhD, Julien De Wolf, MD,

Bronchogenic carcinoma after solid organ transplantation

Invasive Mediastinal Staging Guideline Concordance

Long-Term Outcome after En Bloc Resection of Non–Small-Cell Lung Cancer Invading the Pulmonary Sulcus and Spine Stéphane Collaud, MD, MSc, Thomas K.

Lisa M. Brown, MD, MAS, David T. Cooke, MD, Elizabeth A. David, MD

Andranik Petrosyan, MD, Patrice Bergeron, MD

Long-Term Outcome After Resection of Non-Small Cell Lung Cancer Invading the Thoracic Inlet Stéphane Collaud, MD, MS, Tiago Machuca, MD, PhD, Olaf Mercier,

Multiple Lung Adenocarcinomas Associated With Von Hippel-Lindau Disease Koei Ikeda, MD, PhD, Hironobu Osumi, MD, Kentaro Matsuishi, MD, Eri Matsubara,

Tumor-to-Tumor Metastasis: Maxillary Sinus Adenoid Cystic Carcinoma Metastasizing to Double Primary Lung Adenocarcinoma Wei-Yang Lin, MD, Wen-Hu Hsu,

Yuzhao Wang, MD, Jonathan C. Yeung, MD, PhD, Waël C

Orthotopic Lung Cancer Murine Model by Nonoperative Transbronchial Approach Takahiro Nakajima, MD, PhD, Takashi Anayama, MD, PhD, Yasushi Matsuda, MD,

Eric L. Grogan, MD, MPH, David R. Jones, MD, Benjamin D

How I Teach a Thoracoscopic Lobectomy

Oncological Characteristics of Radiological Invasive Adenocarcinoma with Additional Ground-Glass Nodules on Initial Thin-Section Computed Tomography:

Reply The Annals of Thoracic Surgery

Localization of Pulmonary Nodules Using Navigation Bronchoscope and a Near-Infrared Fluorescence Thoracoscope Takashi Anayama, MD, PhD, Jimmy Qiu, MS,

Cavity Wall Thickness in Solitary Cavitary Lung Adenocarcinomas Is a Prognostic Indicator Yukio Watanabe, MD, Masahiko Kusumoto, MD, Akihiko Yoshida,

Surgical Resection of a Giant Coronary Aneurysm

An Unusual Case of Pleural Chordoma

Katy A. Marino, MD, Jennifer L. Sullivan, MD, Benny Weksler, MD

Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in the Management of Previously Treated Lung Cancer Masaki Anraku, MD, Andrew F. Pierre,

Thoracoscopic localization of intraparenchymal pulmonary nodules using direct intracavitary thoracoscopic ultrasonography prevents conversion of VATS.

Nomogram for Predicting the Risk of Invasive Pulmonary Adenocarcinoma for Pure Ground-Glass Nodules Lijie Wang, MD, Weiyu Shen, MD, Yong Xi, MD, Shuai.

Intraoperative Near-Infrared Fluorescence-Guided Peripheral Lung Tumor Localization in Rabbit Models Hironobu Wada, MD, PhD, Jinzi Zheng, PhD, Alexander.

Use of Single-Cannula Venous-Venous Extracorporeal Life Support in the Management of Life-Threatening Airway Obstruction Michael Ko, MD, Pedro R. dos.

Utility of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in the Diagnosis of Mediastinal Masses of Unknown Etiology Kazuhiro Yasufuku,

Use of Amiodarone After Major Lung Resection

Prognostic Factors for Cure, Recurrence and Long-Term Survival After Surgical Resection of Thymoma Najib Safieddine, MD, Geoffrey Liu, MD, Kris Cuningham,

Stapler-Based Thoracoscopic Basilar Segmentectomy

Primary De Novo Angiosarcoma of the Pleura

Jarrod D. Predina, MD, MTR, Andrew D

Unilateral Absence of the Left Pulmonary Artery Accompanied by Right Lung Cancer Masaoki Ito, MD, Yoshinori Yamashita, MD, PhD, Hiroaki Harada, MD, Ken-ichi.

Unplanned Procedures During Thoracoscopic Segmentectomies

A Multicenter Study of Volumetric Computed Tomography for Staging Malignant Pleural Mesothelioma Valerie W. Rusch, MD, Ritu Gill, MD, Alan Mitchell,

Salvage Operation for Late Recurrence After Stereotactic Body Radiotherapy for Lung Cancer: Two Patients With No Viable Cancer Cells Naohiro Taira, MD,

Identification of a subcentimeter pulmonary adenocarcinoma using intraoperative near- infrared imaging during video-assisted thoracoscopic surgery Jane.

Neurofibromatosis of the Esophagus

Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for Differentiating N0 Versus N1 Lung Cancer Kazuhiro Yasufuku, MD, PhD, Takahiro Nakajima,

High Risk for Thoracotomy but not Thoracoscopic Lobectomy

Extensive Invasion of the Left Atrium by Lung Cancer

Anirudh Vinnakota, MS, Robert Stewart, MD, Gosta Pettersson, MD, PhD

Prognostic Significance of Aberrant Methylation of Solute Carrier Gene Family 5A8 in Lung Adenocarcinoma Koei Ikeda, MD, PhD, Kenji Shiraishi, MD, PhD,

Lymph Node Staging by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Patients With Small Cell Lung Cancer Hironobu Wada, MD, Takahiro.

Impact of Sublobar Resection on Pulmonary Function: Long-Term Results from American College of Surgeons Oncology Group Z4032 (Alliance) Michael S. Kent,

Risk Factors for Major Complications After Extrapleural Pneumonectomy for Malignant Pleural Mesothelioma Marc de Perrot, MD, Karen McRae, MD, Masaki.

Philip A. Linden, MD, Jon O. Wee, MD, Michael T

Video-Assisted Thoracoscopic Surgery for Pulmonary Nodules After Computed Tomography-Guided Marking With a Spiral Wire Uwe Eichfeld, MD, PhD, Arne Dietrich,

Robot-Assisted Thoracoscopic Lobectomy for Early-Stage Lung Cancer

Robert Lee Replogle, September 30, 1931–May 9, 2016

A clinicopathological study of resected adenocarcinoma 2 cm or less in diameter Norihiko Ikeda, MD, PhD, Junichi Maeda, MD, Koichi Yashima, MD, Masahiro.

Mark I. Block, MD The Annals of Thoracic Surgery

Prognostic Role of Subtype Classification in Small-Sized Pathologic N0 Invasive Lung Adenocarcinoma Tomoharu Yoshiya, MD, Takahiro Mimae, MD, PhD, Yasuhiro.

Bronchopulmonary Carcinoid Tumor Associated with Cushing Syndrome

Visceral Pleural Invasion Is Not a Significant Prognostic Factor in Patients With a Part- Solid Lung Cancer Aritoshi Hattori, MD, Kenji Suzuki, MD, Takeshi.

A Small Alveolar Adenoma Resected by Thoracoscopic Surgery

Marcelo Cypel, MD, MSc, Jonathan C

Presentation transcript:

Evaluation of a New Ultrasound Thoracoscope for Localization of Lung Nodules in Ex Vivo Human Lungs Hideki Ujiie, MD, PhD, Tatsuya Kato, MD, PhD, Hsin-pei Hu, MHS, Suhaib Hasan, Priya Patel, MD, Hironobu Wada, MD, PhD, Daiyoon Lee, MS, Kosuke Fujino, MD, PhD, David M. Hwang, MD, PhD, Marcelo Cypel, MD, MS, Marc de Perrot, MD, MS, Andrew Pierre, MD, MS, Gail Darling, MD, Thomas K. Waddell, MD, PhD, Shaf Keshavjee, MD, MS, Kazuhiro Yasufuku, MD, PhD The Annals of Thoracic Surgery Volume 103, Issue 3, Pages 926-934 (March 2017) DOI: 10.1016/j.athoracsur.2016.08.031 Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 (A) Body of the prototype ultrasound thoracoscope (XLTF-UC180; Olympus, Tokyo, Japan). (B) Tip of the ultrasound thoracoscope. The outer diameter is 10 mm for use in minimally invasive surgery. A charge-coupled device camera and two light sources are situated on the tip of the thoracoscope. The accessory channel diameter is 2.2 mm. (C) The ultrasound thoracoscope is placed on the deflated human lung surface to localize lung tumors. The Annals of Thoracic Surgery 2017 103, 926-934DOI: (10.1016/j.athoracsur.2016.08.031) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Comparison of lung adenocarcinoma scanned at the different frequencies in lung specimens (deflated state), with tumor margin visualization at 5 MHz, 7.5 MHz, and 10 MHz, respectively. Higher frequencies produced clearer images. Shallower tumor margins (top) are better visualized at 12 MHz whereas deeper tumor margins (bottom) are better visualized at 10 MHz. White arrows indicate tumor margin. (GGN = ground-glass nodule.) The Annals of Thoracic Surgery 2017 103, 926-934DOI: (10.1016/j.athoracsur.2016.08.031) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Comparison of computed tomography (CT), ultrasonography, and macroscopic (Macro) images between solid nodule and part solid ground-glass nodules (GGN) in both deflated and semiinflated states. Tumor margins are easier to visualize in the deflated state (left) compared with when the lung is semiinflated (right). On CT images, yellow arrows indicate tumor. On ultrasound images, white arrows indicate deepest border of lung tumor. On macroscopic image, white line marks entire tumor margin. The Annals of Thoracic Surgery 2017 103, 926-934DOI: (10.1016/j.athoracsur.2016.08.031) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Comparison of lung adenocarcinoma with computed tomography (CT), ultrasound, and pathology (microscopic) images (deflated state). (Left) Computed tomography images; (middle) ultrasound images (10 MHz); (right) microscopic images (original magnification [top to bottom] ×12, ×7, ×5, and ×5). (A) Lepidic (LEP) predominant adenocarcinoma (ADC). (B) Acinar (ACI) predominant ADC. (C) Papillary (PAP) predominant ADC. (D) Solid (SOL) predominant ADC. The Annals of Thoracic Surgery 2017 103, 926-934DOI: (10.1016/j.athoracsur.2016.08.031) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 (A) Correlation coefficient between ultrasound diameter and actual tumor size (mm). (B) Correlation coefficient between computed tomography (CT) diameter and actual tumor size (mm). The comparison of actual distance from the lung surface to the tumor distal boundary and the distance to the distal boundary on the ultrasound image showed statistically significant and strong correlation (R2 = 0.89, p < 0.001) compared with the actual distance from the lung surface to the tumor distal boundary and the distance to the distal boundary on the CT image (R2 = 0.67, p < 0.001). The Annals of Thoracic Surgery 2017 103, 926-934DOI: (10.1016/j.athoracsur.2016.08.031) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 (A) Comparison between prototype ultrasound thoracoscope (XLTF-UC180 [top]) and laparoscopic ultrasound probe (8666-RF [bottom]). (B) Comparison of ultrasound thoracoscope probe size (top) and laparoscopic ultrasound probe size (bottom). The laparoscopic ultrasound probe is bigger than the ultrasound thoracoscope probe. (C) Comparison of image quality of ultrasound thoracoscope (top panels) and laparoscopic ultrasound (bottom panels) for a solid nodule at different frequencies: left to right, 5 MHz, 7.5 MHz, and 10 MHz. The ultrasound thoracoscope consistently produced clearer images (arrows). The Annals of Thoracic Surgery 2017 103, 926-934DOI: (10.1016/j.athoracsur.2016.08.031) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions