The Apoptosome at High Resolution

Slides:

Advertisements

Similar presentations

Bacterial Nitric Oxide Extends the Lifespan of C. elegans Ivan Gusarov, Laurent Gautier, Olga Smolentseva, Ilya Shamovsky, Svetlana Eremina, Alexander.

Advertisements

The Bacterial DnaC Helicase Loader Is a DnaB Ring Breaker Ernesto Arias-Palomo, Valerie L. O’Shea, Iris V. Hood, James M. Berger Cell Volume 153, Issue.

Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E Yumi Kim, Andrew J. Holland, Weijie Lan, Don W. Cleveland.

SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages (January.

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells Jenny M. Karo, David G. Schatz, Joseph C. Sun Cell Volume.

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity Jenni Durieux, Suzanne Wolff, Andrew Dillin Cell Volume 144, Issue 1, Pages.

Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding J. Winter, M. Ilbert, P.C.F. Graf, D. Özcelik, U. Jakob Cell Volume 135, Issue.

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding Aleksandra Helwak, Grzegorz Kudla, Tatiana Dudnakova, David Tollervey.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

3.3 Å Cryo-EM Structure of a Nonenveloped Virus Reveals a Priming Mechanism for Cell Entry Xing Zhang, Lei Jin, Qin Fang, Wong H. Hui, Z. Hong Zhou Cell.

Treatment of Obesity with Celastrol

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity Michael S. Rooney, Sachet A. Shukla, Catherine J. Wu, Gad Getz,

Growing Dendrites and Axons Differ in Their Reliance on the Secretory Pathway Bing Ye, Ye Zhang, Wei Song, Susan H. Younger, Lily Yeh Jan, Yuh Nung Jan.

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet

Transcriptional Control of Gene Expression by MicroRNAs Basel Khraiwesh, M. Asif Arif, Gotelinde I. Seumel, Stephan Ossowski, Detlef Weigel, Ralf Reski,

Common Sense about Taste: From Mammals to Insects David A. Yarmolinsky, Charles S. Zuker, Nicholas J.P. Ryba Cell Volume 139, Issue 2, Pages (October.

Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm Jianbin Wang, H. Christina Fan, Barry Behr, Stephen.

UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke Jae Young Lee, Wei Yang Cell Volume 127, Issue 7, Pages (December.

Sulfur Amino Acids Regulate Translational Capacity and Metabolic Homeostasis through Modulation of tRNA Thiolation Sunil Laxman, Benjamin M. Sutter, Xi.

Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome Corinne Ferrier Maurice, Henry Joseph Haiser, Peter James Turnbaugh.

Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.

RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity Jean-Baptiste Vannier, Visnja Pavicic-Kaltenbrunner, Mark I.R.

Structurally Distinct Ca2+ Signaling Domains of Sperm Flagella Orchestrate Tyrosine Phosphorylation and Motility Jean-Ju Chung, Sang-Hee Shim, Robert A.

The Monarch Butterfly Genome Yields Insights into Long-Distance Migration Shuai Zhan, Christine Merlin, Jeffrey L. Boore, Steven M. Reppert Cell Volume.

Dynein Anchors Its mRNA Cargo after Apical Transport in the Drosophila Blastoderm Embryo Renald Delanoue, Ilan Davis Cell Volume 122, Issue 1, Pages

Encoding of Both Analog- and Digital-like Behavioral Outputs by One C. elegans Interneuron Zhaoyu Li, Jie Liu, Maohua Zheng, X.Z. Shawn Xu Cell Volume.

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell

Transmembrane Receptor DCC Associates with Protein Synthesis Machinery and Regulates Translation Joseph Tcherkezian, Perry A. Brittis, Franziska Thomas,

Writing Memories with Light-Addressable Reinforcement Circuitry Adam Claridge-Chang, Robert D. Roorda, Eleftheria Vrontou, Lucas Sjulson, Haiyan Li, Jay.

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.

Saturated Fatty Acids Induce c-Src Clustering within Membrane Subdomains, Leading to JNK Activation Ryan G. Holzer, Eek-Joong Park, Ning Li, Helen Tran,

The Metabolic Basis of Pulmonary Arterial Hypertension Gopinath Sutendra, Evangelos D. Michelakis Cell Metabolism Volume 19, Issue 4, Pages (April.

A DNA-Dependent Protease Involved in DNA-Protein Crosslink Repair Julian Stingele, Michael S. Schwarz, Nicolas Bloemeke, Peter G. Wolf, Stefan Jentsch.

Pulsed Forces Timed by a Ratchet-like Mechanism Drive Directed Tissue Movement during Dorsal Closure Jerome Solon, Aynur Kaya-Çopur, Julien Colombelli,

SRC-3 Coactivator Functional Lifetime Is Regulated by a Phospho-Dependent Ubiquitin Time Clock Ray-Chang Wu, Qin Feng, David M. Lonard, Bert W. O'Malley.

WHAMM Is an Arp2/3 Complex Activator That Binds Microtubules and Functions in ER to Golgi Transport Kenneth G. Campellone, Neil J. Webb, Elizabeth A. Znameroski,

Sensory Detection of Food Rapidly Modulates Arcuate Feeding Circuits Yiming Chen, Yen-Chu Lin, Tzu-Wei Kuo, Zachary A. Knight Cell Volume 160, Issue 5,

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.

Unweaving the Autism Spectrum

FUS Zigzags Its Way to Cross Beta

Synovial Sarcoma Mechanisms: A Series of Unfortunate Events

C2 Can Do It, Too Cell Volume 121, Issue 2, Pages (April 2005)

Volume 154, Issue 1, Pages (July 2013)

The Whole (Cell) Is Less Than the Sum of Its Parts

In This Issue Cell Volume 158, Issue 5, (August 2014)

Volume 141, Issue 2, Pages (April 2010)

Volume 129, Issue 4, Pages (May 2007)

The Nematode Death Machine in 3D

Volume 152, Issue 1, (January 2013)

Volume 130, Issue 6, (September 2007)

Volume 143, Issue 6, (December 2010)

Understanding CARD Tricks in Apoptosomes

Making the Most from Changes in Life

Learning from the Uncontrollable

Volume 163, Issue 4, (November 2015)

Immune Cells Exploit a Neural Circuit to Enter the CNS

Volume 163, Issue 2, (October 2015)

Volume 134, Issue 6, (September 2008)

In This Issue Cell Volume 145, Issue 3, (April 2011)

Volume 148, Issue 1, (January 2012)

Targeting Protein Stability with a Small Molecule

Presentation transcript:

The Apoptosome at High Resolution Xinchen Teng, J. Marie Hardwick Cell Volume 141, Issue 3, Pages 402-404 (April 2010) DOI: 10.1016/j.cell.2010.04.015 Copyright © 2010 Elsevier Inc. Terms and Conditions

Figure 1 Structure of CED-4 and Apaf-1 Apoptosomes (A) Conserved domains between Caenorhabditis elegans CED-4 (571 amino acids) and human Apaf-1 (1237 amino acids). (B) The C. elegans CED-4 octamer apoptosome as viewed from the top (upper) and side (lower). (C) Human Apaf-1 heptamer apoptosome as viewed from the top (upper) and side (lower). Cell 2010 141, 402-404DOI: (10.1016/j.cell.2010.04.015) Copyright © 2010 Elsevier Inc. Terms and Conditions