A case report: Ulcerative colitis, treatment with an antibody against tumor necrosis factor (infliximab), and subsequent liver necrosis Urpo Kinnunen,

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A case report: Ulcerative colitis, treatment with an antibody against tumor necrosis factor (infliximab), and subsequent liver necrosis Urpo Kinnunen, Martti Färkkilä, Heikki Mäkisalo Journal of Crohn's and Colitis Volume 6, Issue 6, Pages 724-727 (July 2012) DOI: 10.1016/j.crohns.2012.02.004 Copyright © 2012 European Crohn's and Colitis Organisation Terms and Conditions

Figure 1 Transaminases (AST and ALT), alkaline phosphatase (AFOS) and total bilirubin (BIL) at the time of the Remicade infusions given at 8week intervals. The 3rd infusion was not given because of elevated liver values. Hepatic transplantation was performed 10days later. The laboratory values are represented as times the normal upper limit. Journal of Crohn's and Colitis 2012 6, 724-727DOI: (10.1016/j.crohns.2012.02.004) Copyright © 2012 European Crohn's and Colitis Organisation Terms and Conditions

Figure 2 Panacinar hepatic necrosis with ductular proliferation. H&E staining, original magnification 100×. Journal of Crohn's and Colitis 2012 6, 724-727DOI: (10.1016/j.crohns.2012.02.004) Copyright © 2012 European Crohn's and Colitis Organisation Terms and Conditions