Volume 7, Issue 4, Pages (April 2010)

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Volume 7, Issue 4, Pages 433-437 (April 2010) Atrial fibrillation is independently associated with senile, vascular, and Alzheimer's dementia T. Jared Bunch, MD, J. Peter Weiss, MD, Brian G. Crandall, MD, Heidi T. May, PhD, MSPH, Tami L. Bair, RN, Jeffrey S. Osborn, MD, Jeffrey L. Anderson, MD, Joseph B. Muhlestein, MD, Benjamin D. Horne, PhD, MSPH, Donald L. Lappe, MD, John D. Day, MD, FHRS Heart Rhythm Volume 7, Issue 4, Pages 433-437 (April 2010) DOI: 10.1016/j.hrthm.2009.12.004 Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 1 The incidence of dementia by the patient's AF status. There is a significant increase in dementia in general and in all subtypes in patients with AF. Heart Rhythm 2010 7, 433-437DOI: (10.1016/j.hrthm.2009.12.004) Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 2 Multivariate-adjusted odds ratios based on dementia type and age subgroup. Younger patients who had AF were at higher risk for all types of dementia. The association diminished with advancing age and becomes nonsignificant. Heart Rhythm 2010 7, 433-437DOI: (10.1016/j.hrthm.2009.12.004) Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 3 Multivariate-adjusted hazard ratios for long-term risk of mortality in patients who have dementia and AF. In all forms of dementia, patients with AF have significantly increased rates of total mortality. Heart Rhythm 2010 7, 433-437DOI: (10.1016/j.hrthm.2009.12.004) Copyright © 2010 Heart Rhythm Society Terms and Conditions