Primary Pulmonary Choriocarcinoma Presenting with a Hemothorax

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Primary Pulmonary Choriocarcinoma Presenting with a Hemothorax Hyun-Joo Seol, MD, Ju-Han Lee, MD, Ki Yeol Lee, MD, Je-Hyeong Kim, MD, Nak-Woo Lee, MD, Hyung-Joo Park, MD Journal of Thoracic Oncology Volume 4, Issue 5, Pages 663-665 (May 2009) DOI: 10.1097/JTO.0b013e31819cce6c Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 A, A chest radiograph showing a large right pleural effusion. B, Transvaginal ultrasound reveals no specific findings in the pelvic organs. C, A contrast-enhanced chest computed tomography (CT) showing a large pleural effusion and a thin-walled cystic mass in the right lower lobe (arrow). D, After drainage of the hemothorax, a cystic mass is still visible on CT (arrow). Journal of Thoracic Oncology 2009 4, 663-665DOI: (10.1097/JTO.0b013e31819cce6c) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 A, The cut surface shows a circumscribed hemorrhagic mass involving the pleura. B, Low-magnification microscopy of the choriocarcinoma shows a sheet-like proliferation of atypical cytotrophoblasts (arrow) and scattered syncytiotrophoblasts (arrow head) with hemorrhage (hematoxylin-eosin, original magnification ×100). C, Tumor cells stain strongly immune-positive for β-hCG (original magnification ×100). D, High magnification of the tumor cells shows marked nuclear and cellular atypia and increased mitotic activity (arrow) (hematoxylin-eosin, original magnification ×400). Journal of Thoracic Oncology 2009 4, 663-665DOI: (10.1097/JTO.0b013e31819cce6c) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions