Factors Influencing HLA Sensitization in Implantable LVAD Recipients

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Factors Influencing HLA Sensitization in Implantable LVAD Recipients Malek G Massad, Daniel J Cook, Steven K Schmitt, Nicholas G Smedira, James F McCarthy, Rita L Vargo, Patrick M McCarthy The Annals of Thoracic Surgery Volume 64, Issue 4, Pages 1120-1125 (October 1997) DOI: 10.1016/S0003-4975(97)00807-2

Fig. 1 Frequency of human leukocyte antigen (HLA) sensitization in left ventricular assist device (LVAD) recipients. (PRE-LVAD = before LVAD; PEAK LVAD = peak level of panel-reactive antigen [PRA] during LVAD support; LVAD TX = at time of transplantation.) The Annals of Thoracic Surgery 1997 64, 1120-1125DOI: (10.1016/S0003-4975(97)00807-2)

Fig. 2 Mean panel-reactive antigen (PRA) levels showed significant increase during left ventricular assist device (LVAD) support and at the time of transplantation (TX). The Annals of Thoracic Surgery 1997 64, 1120-1125DOI: (10.1016/S0003-4975(97)00807-2)

Fig. 3 Mean panel-reactive antigen (PRA) levels of left ventricular assist device (LVAD) recipients compared with the median number of blood products transfused before transplantation (TX). The Annals of Thoracic Surgery 1997 64, 1120-1125DOI: (10.1016/S0003-4975(97)00807-2)

Fig. 4 Effect of leukocyte depletion (LD) and cytomegalovirus (CMV) status of transfused platelet (PLTS) concentrates on mean panel-reactive antigen (PRA) levels during left ventricular assist device (LVAD) support and at the time of transplantation. (NEG = negative; ? = unknown status.) The Annals of Thoracic Surgery 1997 64, 1120-1125DOI: (10.1016/S0003-4975(97)00807-2)