Is Instability Good for the Brain?

Slides:



Advertisements
Similar presentations
The Neurobiology of Decision: Consensus and Controversy Joseph W. Kable, Paul W. Glimcher Neuron Volume 63, Issue 6, Pages (September 2009) DOI:
Advertisements

Treating the Developing versus Developed Brain: Translating Preclinical Mouse and Human Studies B.J. Casey, Charles E. Glatt, Francis S. Lee Neuron Volume.
NMDA Receptors in Dopaminergic Neurons Are Crucial for Habit Learning Lei Phillip Wang, Fei Li, Dong Wang, Kun Xie, Deheng Wang, Xiaoming Shen, Joe Z.
Preference Distributions of Primary Motor Cortex Neurons Reflect Control Solutions Optimized for Limb Biomechanics Timothy P. Lillicrap, Stephen H. Scott.
The Pathobiology of Vascular Dementia Costantino Iadecola Neuron Volume 80, Issue 4, Pages (November 2013) DOI: /j.neuron Copyright.
Decision Making as a Window on Cognition Michael N. Shadlen, Roozbeh Kiani Neuron Volume 80, Issue 3, Pages (October 2013) DOI: /j.neuron
Contour Saliency in Primary Visual Cortex Wu Li, Valentin Piëch, Charles D. Gilbert Neuron Volume 50, Issue 6, Pages (June 2006) DOI: /j.neuron
Neuronal Cell Types and Connectivity: Lessons from the Retina H. Sebastian Seung, Uygar Sümbül Neuron Volume 83, Issue 6, Pages (September 2014)
Single Units in the Medial Prefrontal Cortex with Anxiety-Related Firing Patterns Are Preferentially Influenced by Ventral Hippocampal Activity Avishek.
Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease Nobutaka Hirokawa, Shinsuke Niwa, Yosuke Tanaka.
Synapse-Specific Adaptations to Inactivity in Hippocampal Circuits Achieve Homeostatic Gain Control while Dampening Network Reverberation Jimok Kim, Richard.
Pyramidal Neurons Grow Up and Change Their Mind Gord Fishell, Carina Hanashima Neuron Volume 57, Issue 3, Pages (February 2008) DOI: /j.neuron
Hippocampal Activity Patterns Carry Information about Objects in Temporal Context Liang-Tien Hsieh, Matthias J. Gruber, Lucas J. Jenkins, Charan Ranganath.
Dissociable Medial Prefrontal Contributions to Judgments of Similar and Dissimilar Others Jason P. Mitchell, C. Neil Macrae, Mahzarin R. Banaji Neuron.
Mechanisms of Age-Related Macular Degeneration Jayakrishna Ambati, Benjamin J. Fowler Neuron Volume 75, Issue 1, Pages (July 2012) DOI: /j.neuron
Adaptation to Natural Binocular Disparities in Primate V1 Explained by a Generalized Energy Model Ralf M. Haefner, Bruce G. Cumming Neuron Volume 57, Issue.
Reading the Book of Memory: Sparse Sampling versus Dense Mapping of Connectomes H. Sebastian Seung Neuron Volume 62, Issue 1, Pages (April 2009)
Rare Inherited Variation in Autism: Beginning to See the Forest and a Few Trees Jason L. Stein, Neelroop N. Parikshak, Daniel H. Geschwind Neuron Volume.
Neuronal Synchronization along the Dorsal Visual Pathway Reflects the Focus of Spatial Attention Markus Siegel, Tobias H. Donner, Robert Oostenveld, Pascal.
Building Better Models of Visual Cortical Receptive Fields
Xiao-Bing Gao, Tamas L. Horvath  Neuron 
Paul M. George, Gary K. Steinberg  Neuron 
Jochen G. Schneider, Joseph H. Nadeau  Cell Metabolism 
Kelly Howell, Oliver Hobert  Neuron 
Axonally Translated SMADs Link Up BDNF and Retrograde BMP Signaling
In Search of the Ever-Elusive Positive Endozepine
PDF Has Found Its Receptor
Alexander Stein, Reinhard Jahn  Neuron 
Let Music Sound while She Doth Make Her Choice
Calcium Signaling and the Control of Dendritic Development
Volume 21, Issue 2, Pages (August 2017)
Calcium Signals Control Wnt-Dependent Dendrite Growth
Xiao-Bing Gao, Tamas L. Horvath  Neuron 
Hippocalcin: A New Solution to an Old Puzzle
Parkinson’s Disease: A Thalamostriatal Rebalancing Act?
Searching for Signatures of Brain Maturity: What Are We Searching For?
Can One Suppress Subliminal Words?
Vincent D. Costa, Peter H. Rudebeck  Neuron 
Volume 73, Issue 1, Pages 1-3 (January 2012)
Metabolic Networks of Longevity
Volume 68, Issue 2, Pages (October 2010)
Following Directions from the Retina to the Brain
Huntington's Disease: Can Mice Lead the Way to Treatment?
Recurrent Feedback Loops in Associative Learning
Making Choices between Rules or between Actions
A Remarkable Facilitating Effect of Parietal Damage
Bringing Kids into the Scientific Review Process
Nob Mice Wave Goodbye to Eye-Specific Segregation
MicroRNAs in Memory Processing
The Strange Case of Aggression and the Brain
The Ribosome Emerges from a Black Box
Synapses and Growth Cones on Two Sides of a Highwire
Searching for Signatures of Brain Maturity: What Are We Searching For?
Watching the Fly Brain Learn
Vincent D. Costa, Peter H. Rudebeck  Neuron 
The Strange Case of Aggression and the Brain
Beta and Gamma Rhythms Go with the Flow
Brain Canada: One Brain One Community
Satb2 Stations Neurons along Reflex Arcs
NO Signals from the Cancer Stem Cell Niche
Superior Colliculus Does Play Dice
Role reversal: Brain insulin and liver STAT3
The Cost of Brain Diseases: A Burden or a Challenge?
In Search of the Ever-Elusive Positive Endozepine
The Dopamine D2 Receptor: New Surprises from an Old Friend
Brain Canada: One Brain One Community
Santosh Kesari, Charles D. Stiles  Neuron 
David Hubel and Torsten Wiesel
Medial Prefrontal Cortex Updates Its Status
Nicolas Unsain, Philip A. Barker  Neuron 
Presentation transcript:

Is Instability Good for the Brain? Robert A. Carrillo, Kaushiki Menon, Kai Zinn  Neuron  Volume 77, Issue 4, Pages 599-601 (February 2013) DOI: 10.1016/j.neuron.2013.02.002 Copyright © 2013 Elsevier Inc. Terms and Conditions

Figure 1 Molecules and Processes Involved in Spartin/BMP/Microtubule Stability Pathways Red boxes indicate negative influences, and green boxes positive influences. Components examined by Nahm et al. (2013) are in italics, and blue lines represent the novel links they identified. It has not been determined whether Spartin is also involved in endocytosis of other BMP receptors (bar labeled “?”). Other links are from the work of many other groups, not all of whom could be individually cited due to space limitations. Abbreviations: Hiw, Highwire; Daw/Babo, Dawdle/Baboon; aPKC, atypical protein kinase C; FoxO, Forkhead Box protein, class O. Neuron 2013 77, 599-601DOI: (10.1016/j.neuron.2013.02.002) Copyright © 2013 Elsevier Inc. Terms and Conditions