Clinical marker confirmation using centrally assessed progression-free survival data in patients with advanced non-small cell lung cancer with non-squamous.

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Clinical marker confirmation using centrally assessed progression-free survival data in patients with advanced non-small cell lung cancer with non-squamous histology treated in LUME-Lung 2. Clinical marker confirmation using centrally assessed progression-free survival data in patients with advanced non-small cell lung cancer with non-squamous histology treated in LUME-Lung 2. Treatment-by-covariate interaction tests for HRs using data from patients treated with nintedanib–pemetrexed. LDH, lactate dehydrogenase. aHRs and CIs obtained from a model stratified by Eastern Cooperative Oncology Group performance status (0 vs ≥1), brain metastases at baseline (yes vs no), prior treatment with bevacizumab (yes vs no) and tumour histology (adenocarcinoma vs non-adenocarcinoma). Birgit Gaschler-Markefski et al. ESMO Open 2017;2:e000102 Copyright © European Society for Medical Oncology. All rights reserved.