European guidelines for diagnosis and management of patients with suspected herpes simplex encephalitis Paul E. Klapper, Graham M. Cleator Clinical Microbiology and Infection Volume 4, Issue 4, Pages 178-180 (April 1998) DOI: 10.1111/j.1469-0691.1998.tb00665.x Copyright © 1998 European Society of Clinical Infectious Diseases Terms and Conditions
Figure 1 Diagnostic algorithm for management of patients with suspected HSE (reproduced, with permission, from J Neurol Neurosurg Psychlatry 1996; 61: 339–45). As patients may present with raised intracranial pressure, immediate lumbar puncture may not be possible. In these circumstances, commencement of acyclovir therapy prior to lumbar puncture is warranted. Clinical Microbiology and Infection 1998 4, 178-180DOI: (10.1111/j.1469-0691.1998.tb00665.x) Copyright © 1998 European Society of Clinical Infectious Diseases Terms and Conditions