Bone shape does not cause OA – But OA does change bone shape; a study on data from 4654 knees from the Osteoarthritis Initiative M.A. Bowes, C.B. Wolstenholme,

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Presentation transcript:

Bone shape does not cause OA – But OA does change bone shape; a study on data from 4654 knees from the Osteoarthritis Initiative M.A. Bowes, C.B. Wolstenholme, G.R. Vincent, P.G. Conaghan Osteoarthritis and Cartilage Volume 24, Pages S259-S260 (April 2016) DOI: 10.1016/j.joca.2016.01.492 Copyright © 2016 Terms and Conditions

Figure 1. Standardized coefficients for explanatory variable in on ANCOVA model of bone area slope (expressed as percent of baseline area) Osteoarthritis and Cartilage 2016 24, S259-S260DOI: (10.1016/j.joca.2016.01.492) Copyright © 2016 Terms and Conditions

Figure 2. Distribution of 6-year slope in MF bone area, using all available knees from the OAI which had images at 0,1,2,4 and 6-year time points Note: pace of change for population quickens with increasing KL grade, and SD of distribution increases Osteoarthritis and Cartilage 2016 24, S259-S260DOI: (10.1016/j.joca.2016.01.492) Copyright © 2016 Terms and Conditions