Chapter 27: Drugs for Lipid Disorders

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Chapter 27: Drugs for Lipid Disorders DISCUSSION POINTS Chapter 27: Drugs for Lipid Disorders Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved.

Types of Lipids - Triglycerides - Phospholipids - Steroids Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved.

- High-density lipoprotein (HDL) - Low-density lipoprotein (LDL) Lipoproteins - High-density lipoprotein (HDL) - Low-density lipoprotein (LDL) - Very low-density lipoprotein (VLDL) Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved.

Discuss the teaching needs for the patient in the following scenario: A client has been taking atorvastatin calcium (Lipitor) 80 mg daily for eight weeks. The blood lipid levels are still elevated. The physician finds out the client is eating a lot of foods high in cholesterol and saturated fats. The client states, “I thought that ‘pill’ was to take care of everything.” Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved.

Discuss the rationale for patients requiring an antihyperlipidemic agent even though they have reduced their dietary intake of cholesterol and saturated fats. Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved.

HMG CoA reductase inhibitor - Best time of day to take - Reason for this timing Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved.

The rationale why patients should not self-medicate with OTC niacin to lower blood lipid levels Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved.

The reasons that patients must wait a month or more to see the effects of lipid-lowering agents Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved.

The rationale behind why HMG CoA reductase inhibitors are contraindicated in patients with liver dysfunction Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved.