Marjolin’s Ulcer of the Pleural Surface Within a Long-Standing Eloesser Flap Jennifer A. Foster, BS, Pratibha Shukla, MD, Omar Azar, MD, Timothy Lee,

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Presentation transcript:

Marjolin’s Ulcer of the Pleural Surface Within a Long-Standing Eloesser Flap Jennifer A. Foster, BS, Pratibha Shukla, MD, Omar Azar, MD, Timothy Lee, MD, Joanna Sesti, MD, Jessica S. Donington, MD The Annals of Thoracic Surgery Volume 102, Issue 5, Pages e383-e385 (November 2016) DOI: 10.1016/j.athoracsur.2016.04.004 Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Axial chest computed tomography image demonstrating the revised pleural window posteriorly, as well as bony destruction and an overlying fluid collection anteriorly. The Annals of Thoracic Surgery 2016 102, e383-e385DOI: (10.1016/j.athoracsur.2016.04.004) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Intraoperative photograph looking from the posterior window toward the inner aspect of the anterior chest wall adjacent to the area of seventh and eighth rib debridement and demonstrating the nodular appearance of the pleural surface. The Annals of Thoracic Surgery 2016 102, e383-e385DOI: (10.1016/j.athoracsur.2016.04.004) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 (A) Hematoxylin and eosin–stained pleural biopsy sample (magnification ×10) shows moderately differentiated to well-differentiated invasive squamous cell carcinoma with keratinization of the pleural surface. At (B) magnification ×10 and (C) magnification ×40, biopsy samples stained with hematoxylin and eosin demonstrate well-differentiated invasive squamous carcinoma associated with sheets and clusters of highly pleomorphic, polygonal to spindle cells in the adjacent stroma. (D) This p63 immunohistochemistry stained mediastinal biopsy sample (magnification ×10), shows nuclear staining of pleomorphic stromal cells. The Annals of Thoracic Surgery 2016 102, e383-e385DOI: (10.1016/j.athoracsur.2016.04.004) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions