Jan Philipp Junker, Alexander van Oudenaarden Molecular Cell

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Presentation transcript:

When Noisy Neighbors Are a Blessing: Analysis of Gene Expression Noise Identifies Coregulated Genes Jan Philipp Junker, Alexander van Oudenaarden Molecular Cell Volume 45, Issue 4, Pages 437-438 (February 2012) DOI: 10.1016/j.molcel.2012.02.002 Copyright © 2012 Elsevier Inc. Terms and Conditions

Figure 1 Networks and Correlations (A) Gene expression noise is transmitted from an upstream regulator to a downstream target. Expression levels of the target in individual cells will depend on the intensity of the regulator signal in the respective cell. (B) In a population of cells, genes belonging to the same regulatory network will be correlated among each other (green arrows) but not to genes controlled by other pathways (gray arrow). Molecular Cell 2012 45, 437-438DOI: (10.1016/j.molcel.2012.02.002) Copyright © 2012 Elsevier Inc. Terms and Conditions