Fernando Fernández-Bañares, Antonio Salas, Maria Esteve

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Presentation transcript:

Pitfalls and errors in the diagnosis of collagenous and lymphocytic colitis Fernando Fernández-Bañares, Antonio Salas, Maria Esteve Journal of Crohn's and Colitis Volume 2, Issue 4, Pages 343-347 (December 2008) DOI: 10.1016/j.crohns.2008.05.010 Copyright © 2008 European Crohn's and Colitis Organisation Terms and Conditions

Figure 1 Collagenous colitis: A. — Trichromic stain. There is a thickened abnormal surface subepithelial collagen layer, which entraps superficial capillaries and with an irregular lacy appearance of the lower edge of the basement membrane; B. — Immunohistochemistry for tenascin expression allows a better detection of the thickened subepithelial collagen layer in doubtful cases. Journal of Crohn's and Colitis 2008 2, 343-347DOI: (10.1016/j.crohns.2008.05.010) Copyright © 2008 European Crohn's and Colitis Organisation Terms and Conditions

Figure 2 Lymphocytic colitis. Damage of surface epithelium with flattening of epithelial cells and increased number of intraepithelial lymphocytes. Increased chronic inflammatory infiltrate in the lamina propria. Journal of Crohn's and Colitis 2008 2, 343-347DOI: (10.1016/j.crohns.2008.05.010) Copyright © 2008 European Crohn's and Colitis Organisation Terms and Conditions

Figure 3 Frequency of the different clinical symptoms at diagnosis on a population-based cohort of microscopic colitis patients.3 Journal of Crohn's and Colitis 2008 2, 343-347DOI: (10.1016/j.crohns.2008.05.010) Copyright © 2008 European Crohn's and Colitis Organisation Terms and Conditions