THE HEART AS A PUMP REGULATION OF CARDIAC OUTPUT

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Presentation transcript:

THE HEART AS A PUMP REGULATION OF CARDIAC OUTPUT Heart Rate via sympathetic & parasympathetic nerves Stroke Volume Frank-Starling “Law of the Heart” Changes in Contractility MYOCARDIAL CELLS (FIBERS) Regulation of Contractility Length-Tension and Volume-Pressure Curves The Cardiac Function Curve

Autoregulation (Frank-Starling “Law of the Heart”) CARDIAC OUTPUT = STROKE VOLUME x HEART RATE Contractility Sympathetic Nervous System Parasympathetic Nervous System

CARDIAC FUNCTION CURVE THE FRANK- STARLING “LAW OF THE HEART” 15- Increased Contractility 10- CARDIAC OUTPUT (L/min) 5- -4 +4 +8 RAP mmHg

WORK OUTPUT OF THE HEART 1.VOLUME PRESSURE CURVE 2.REGULATION OF HEART PUMPING A.FRANK-STARLING MECHANISM B.AUTONOMIC NERVOUS SYSTEM C.CALCIUM AND POTASSIUM D.EFFECT OF TEMERATURE 4

Pressure Volume Loop Late Systole

Pressure Volume Loop Early Diastole

Pressure Volume Loop Late Diastole

Pressure Volume Loop End Diastole 11

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