Low Cost Fundus Camera P15590 October 28th, 2014 Presented by: Daniel Sui, Ian Morency, Kevin Labourdette, Kyle Burden, Thomas Casero, Quang Huynh October 28th, 2014 Kyle

Overview High Risk in Optical Systems Outside Help Alignment Designed, but needs testing Overarching Design Improved Microcontroller Stepper Motors System Power Kyle

Optical Design Research - Kevin Main Subsystem Highest Importance Highest Risk Kevin

Subsystems - Kevin Three Main Subsystems Imaging Create image of cornea Create image of pupil Adjust for magnification and focus Illumination IR illumination for video feed LED flash for photos Needs to be collimated, perfectly on axis, and adjustable Targeting Align pupil to imaging subsystem Kevin

Imaging/Illumination Subsystems - Kevin

Targeting Subsystem - Tommy Aligns Photographed Eye Non-scanned eye Multi-target screen Bi convex lens Red Illumination Kevin/Tommy Discuss this?

Optical Design Risks - Ian Reflections Main Issue in current systems Usually solved with pupil dilations Donut shaped light Scatters light out of system Not always effective Ian

Optical Design Risks - Tommy Cost Most likely will require multiple revisions Need access to optical design software Access to optical bench and opto-mechanical mounting components Tommy

Meeting with Expert 1 - Kevin Nicholas Lovullo Optical Designer at Raytheon U of R grad in Optical Engineering Discussed current research via Phone Kevin

Meeting with Expert 1 - Kevin Takeaways Will need to fully research and understand optical properties of the eye Basic system layout is correct Not a simple system to design Will require a lot more than a few calculations Kevin

Meeting with Expert 2 - Kevin Josh Cobb Senior Optical Engineer at Corning Tropel PhD in Optical Engineering Has experience designing an ocular fundus camera Discussed best ways to begin optical design - in person mtg Kevin

Meeting with Expert 2 - Kevin Takeaways The optical design is extremely complicated - even for experts in the field Optical design and testing is impossible on current budget We will need to copy an existing design or partner with optical engineers Julie Bentley Kevin

Meeting with Expert 3 - Tommy Julie Bentley Professor at U of R PhD in Optical Engineering Discussed possibility of partnering - in person meeting Tommy

Meeting with Expert 3 - Tommy Takeaways Many of the same concerns including budget and complexity Already assigned senior design projects ~3 weeks prior Will be hard to design to only use off the shelf optics Alternative would take years, over $50,000 Introduced us to Pedro Ramirez Tommy

Meeting with Pedro Ramirez - Ian Optical Design Student at U of R Experience imaging retina and cornea Retinal Topography Corneal Aberrations Excited to help with project Will help create optical design Follow up meeting with entire team - 10/30 Ian

Optical Design - Next Steps - Ian Catch Pedro up on project in detail Develop detailed list of specifications for optical system Camera Quality Wavelengths Etc Work to receive more funding Design Center Client Ian

Alignment System - Tommy Internal Fixation Eyes move in tandem One eye focuses Other eye is imaged Benefits Fewer components Wide FOV Tommy

Internal Fixation Needs - Tommy X-axis movement Compensate for introduced angles Small movements needed, millimeters Manual hand knob controls 2 Lens Sets Larger lens that can drop away for full eye imaging Optics set for retinal imaging Camera is z-axis stationary Lenses must focus and magnify in z-axis Tommy

Internal Fixation Notes - Tommy Lens/Camera Lens must NOT be coated No camera hot mirror These reflect IR light Focus IR and natural light focus differently Differential is well-known Tommy

Overarching Design - Ian Black Box Method 95% of people Obesity Large Bust Elderly Ian

Overarching Design - Ian Easily move Camera to patient Sedentary Reclined Angled Flexible Portable Ian

Arduino Uno - Dan Rev 3 (2010) Atmel 16U2 microprocessor 14 digital I/O pins, 6 with PWM output 6 Analog Input Pins Standard USB port C/C++ sketch Cost: $22.99 Arducam Shield Model OV5642: 5MP 1080p video Cost: $29.99 shield, $29.99 5MP camera Dan programmed in Java

Raspberry Pi - Quang Model B+ 512 MB RAM Small Computer 40 GPIO pins 4 USB ports HDMI port Cost: $39.95 Raspberry Pi Camera Module 5 MP Supports 1080p video Cost: $29.95 Quang Programmed with python

Beaglebone - Kyle Beaglebone Black Rev C Pre-loaded with Debian Linux 512 MB onboard RAM 4GB of eMMC built-in storage USB, micro-HDMI, Ethernet two 46-pin headers Cost: $55.00 Kyle Can be programmed with C/C++, Python, Java, Ruby, etc...

Which Microcontroller? - Kyle Raspberry Pi B+ Decent price! Lots of I/O pins and USB ports! Cheaper Camera Module More options Can test out Raspberry Pi, possibly w/ camera module, and Beaglebone in CE Labs before purchasing Cost: MCU - $39.95 Camera Module - $29.95 Pi TFT - $34.95 Total - $104.85 Kyle Talked with Dr. Becker. Also talked with Dr. Kawinski about which communication is best

Raspberry Pi with Touchscreen - Kyle Adafruit PiTFT 2.8” screen 320 x 240 Cost: $34.95 Tindie PiScreen 3.5” screen - slim 480 x 320 Cost: $56.95 Kyle

Servo Motor - Dan Control angle/position with PWM 555 timing chip Arduino Uno: 500 mA limit 1 degree precision Motor torque Size of lens Linear precision Tower Pro SG-5010 4.8V to 6V 5.39 N-mm Cost: $12.00 Dan

Stepper Motor - Quang Small Reduction Stepper Motor 5 VDC 8 steps per rev 1/64 gear reduction Holding torque : 15 N * mm Additional Components L293D - Dual H-Bridge Motor Driver Breakout + cable Quang Total Cost: $13.95

System Power - Quang Raspberry Pi Controller Requires 5V, ~700mA Powered from micro USB connection Solution Buy Micro USB power supply charger Cost: $6.81 Camera & Motors Powered by Raspberry Pi Quang

Summary High Risk in Optical Systems Outside Help Alignment Designed, but needs testing Overarching Design Improved Microcontroller Stepper Motors System Power Kyle

Questions