Escaping the Valley of Death Robert M Frederickson Molecular Therapy Volume 20, Issue 3, Pages 476-478 (March 2012) DOI: 10.1038/mt.2012.21 Copyright © 2012 The American Society of Gene & Cell Therapy Terms and Conditions
Figure 1 Development of complex biological therapies (CBTs). The “valley of death” refers to the critical period between preclinical validation and clinical evaluation of CBTs, as a result of the drop-off in academic funding and the complex regulatory requirements. Courtesy of Malcolm K. Brenner, Baylor College of Medicine. Molecular Therapy 2012 20, 476-478DOI: (10.1038/mt.2012.21) Copyright © 2012 The American Society of Gene & Cell Therapy Terms and Conditions