Immune Checkpoint Immunotherapy for Non-Small Cell Lung Cancer

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Presentation transcript:

Immune Checkpoint Immunotherapy for Non-Small Cell Lung Cancer Karthik Suresh, MD, Jarushka Naidoo, MBBCh, Cheng Ting Lin, MD, Sonye Danoff, MD, PhD CHEST Volume 154, Issue 6, Pages 1416-1423 (December 2018) DOI: 10.1016/j.chest.2018.08.1048 Copyright © 2018 American College of Chest Physicians Terms and Conditions

Figure 1 Schematic showing the actions of checkpoint PD-1 and its ligands PD-L1 in untreated and ICI-treated NSCLC. Ag = antigen; APC = antigen-presenting cell; ICI = immune checkpoint immunotherapy; NSCLC = non-small cell lung cancer; PD-1 = programmed death-1; PD-L1 = programmed death-ligand 1; TCR = T-cell receptor. CHEST 2018 154, 1416-1423DOI: (10.1016/j.chest.2018.08.1048) Copyright © 2018 American College of Chest Physicians Terms and Conditions