Selective arterialization of a cardiac vein in a model of cardiac microangiopathy and macroangiopathy in sheep Michaela Elisabeth Resetar, MD, Cris Ullmann,

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Presentation transcript:

Selective arterialization of a cardiac vein in a model of cardiac microangiopathy and macroangiopathy in sheep Michaela Elisabeth Resetar, MD, Cris Ullmann, Petra Broeske, Kristin Ludwig-Schindler, Nicolas K. Doll, MD, PhD, Aida Salameh, MD, Stefan Dhein, MD, PhD, Friedrich W. Mohr, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 133, Issue 5, Pages 1252-1256 (May 2007) DOI: 10.1016/j.jtcvs.2006.12.037 Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Angiograms taken during the experiment: The angiographic catheter is introduced into the LCA where contrast fluid is injected, which fills the LCA and its branches, the Ramus circumflexus, and the LAD without any pathologic changes (A) at the beginning of the experiment and with stenosis (B). The transonic flow probe is placed on the ascending aorta, and a catheter for measurement of changes of left ventricular volume is introduced (not used in this experiment). C, The contrast fluid has filled the left internal thoracic artery, and after passing the anastomosis, the cardiac vein that accompanies the LAD artery. There is a connection (*) of this vein with a venous vessel on the back of the heart (posterior cardiac vein). A clamp (C), used for fixation, is also visible. LCA, left coronary artery. The Journal of Thoracic and Cardiovascular Surgery 2007 133, 1252-1256DOI: (10.1016/j.jtcvs.2006.12.037) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Limb lead II is chosen to demonstrate the normal ECG at the start of the experiment (A), the elevation of the ST segment after injection of the microspheres (B), its progression after stenosis of the LAD artery (C), the regression of the ST segment elevations after establishing venous revascularization (D), and its return to nearly normal after reopening the LAD artery (E). ECG, electrocardiogram; LAD, left anterior descending. The Journal of Thoracic and Cardiovascular Surgery 2007 133, 1252-1256DOI: (10.1016/j.jtcvs.2006.12.037) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions