Ventilation–perfusion distributions and gas exchange during carbon dioxide- pneumoperitoneum in a porcine model C.M. Strang, F Fredén, E Maripuu, T Hachenberg,

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Ventilation–perfusion distributions and gas exchange during carbon dioxide- pneumoperitoneum in a porcine model C.M. Strang, F Fredén, E Maripuu, T Hachenberg, G Hedenstierna British Journal of Anaesthesia Volume 105, Issue 5, Pages 691-697 (November 2010) DOI: 10.1093/bja/aeq211 Copyright © 2010 The Author(s) Terms and Conditions

Fig 1 SPECT: ventilation and blood flow distributions in the caudal-to-cranial direction (horizontal axis) during anaesthesia before (a) and during PP (b). Ventilation (V) and blood flow (Q) are shown in per cent of their peak values. Note the shift of ventilation and perfusion away from the caudal region after induction of PP and the balanced V/Q distribution. (Mean+sd of all seven pigs studied with SPECT.) British Journal of Anaesthesia 2010 105, 691-697DOI: (10.1093/bja/aeq211) Copyright © 2010 The Author(s) Terms and Conditions

Fig 2 SPECT: ventilation and blood flow distributions from dorsal to ventral (vertical axis) during anaesthesia before (a) and during PP (b). Ventilation (V) and blood flow (Q) are shown in per cent of their peak values. ‘Area A’, as described in the Results section, is shown in both panels. Note the larger difference in ventilation and perfusion distributions than in the caudal-to-cranial direction shown in Figure 1. Note also the smaller area A during PP, indicating less of ‘over-perfused’ areas relative to their ventilation. This should improve oxygenation when compared with the recording during baseline before PP. [Mean (sd) of all seven pigs studied with SPECT.] British Journal of Anaesthesia 2010 105, 691-697DOI: (10.1093/bja/aeq211) Copyright © 2010 The Author(s) Terms and Conditions

Fig 3 MIGET: ventilation and blood flow plotted against VA/Q ratios during anaesthesia (a) and after creation of PP (b). Note the slight decrease in shunt and closer matching of ventilation and blood flow distributions during PP (see also Vmean and Qmean in Table 2). British Journal of Anaesthesia 2010 105, 691-697DOI: (10.1093/bja/aeq211) Copyright © 2010 The Author(s) Terms and Conditions