M. Zaar, B. Lauritzen, N. H. Secher, T. Krantz, H. B. Nielsen, P. L

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Presentation transcript:

Initial administration of hydroxyethyl starch vs lactated Ringer after liver trauma in the pig M. Zaar, B. Lauritzen, N.H. Secher, T. Krantz, H.B. Nielsen, P.L. Madsen, P.I. Johansson British Journal of Anaesthesia Volume 102, Issue 2, Pages 221-226 (February 2009) DOI: 10.1093/bja/aen350 Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

Fig 1 Blood loss, Hb, CO, MAP, and heart rate of pigs (n=7, in each group) during administration of HES or with RL and HES (P3) after a Grade III crush and avulsion liver trauma. Dotted lines, fluid resuscitation phases: P1, 0.7 ml kg−1 min−1; P2, 1.65 ml kg−1 min−1; and P3, according to blood loss. Data are normalized and presented as mean (sem). *Different from baseline (P<0.05). †Difference in total blood loss between the groups (P<0.01). British Journal of Anaesthesia 2009 102, 221-226DOI: (10.1093/bja/aen350) Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

Fig 2 Oxygen delivery and uptake for pigs during administration of (a) HES (P1–3; n=6) or (b) RL (P1–2; n=7) and HES (P3) following a Grade III crush and avulsion liver trauma. P1, 0.7 ml kg−1 min−1; P2, 1.65 ml kg−1 min−1; and P3, according to blood loss. Data are normalized and presented as mean (sem). *Different from baseline (P<0.05). British Journal of Anaesthesia 2009 102, 221-226DOI: (10.1093/bja/aen350) Copyright © 2009 British Journal of Anaesthesia Terms and Conditions