Halofuginone to treat fibrosis in chronic graft-versus-host disease and scleroderma Mark Pines, David Snyder, Shai Yarkoni, Arnon Nagler Biology of Blood and Marrow Transplantation Volume 9, Issue 7, Pages 417-425 (July 2003) DOI: 10.1016/S1083-8791(03)00151-4
Figure 1 Collagen α1(I) gene expression. Skin biopsies were taken from the posterior upper back of the cGvHD patient before (A) and 6 months after (B) topical halofuginone therapy. The sections were hybridized with digoxigenin-labeled collagen α1(I) probe. Note the reduction in cells expressing the collagen α1(I) gene (arrows). Biology of Blood and Marrow Transplantation 2003 9, 417-425DOI: (10.1016/S1083-8791(03)00151-4)