Adrian Fine, James Zacharias  Kidney International 

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Presentation transcript:

Calciphylaxis is usually non-ulcerating: Risk factors, outcome and therapy  Adrian Fine, James Zacharias  Kidney International  Volume 61, Issue 6, Pages 2210-2217 (June 2002) DOI: 10.1046/j.1523-1755.2002.00375.x Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 1 Patterns of calciphylaxis.(A) Classical presentation with calf plaques (often confluent), the borders of which are shown with arrows. Parts of the skin are erythematous, which is easily confused with simple cellulitis. (B) Gross ulceration (in the same patient 3 months later). The black eschar has been surgically débrided. (C) Calciphylactic rash on an arm. (D) Calciphylactic rash on abdomen with 2 to 3cm ulcers, with close-up view of lesions (E). Kidney International 2002 61, 2210-2217DOI: (10.1046/j.1523-1755.2002.00375.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 2 Bone scan abnormalities in calciphylaxis. (A) Classical calf calcification. (B) There is strongly positive lung calcification but negative uptake in lower legs. At the time of the scan, both lower legs had gross ulceration from popliteal fossa to ankles. Other types are discussed in the Results section. Kidney International 2002 61, 2210-2217DOI: (10.1046/j.1523-1755.2002.00375.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 3 Patterns of x-ray abnormalities in calciphylaxis. (A) Diffuse reticular pattern (with heavily calcified vessels). (B) Gross confluent patches of calcification. Other variants are discussed in the Results section. Kidney International 2002 61, 2210-2217DOI: (10.1046/j.1523-1755.2002.00375.x) Copyright © 2002 International Society of Nephrology Terms and Conditions