Figure 4 Gross and histopathological characteristics of cardiac myxoma

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Figure 4 Gross and histopathological characteristics of cardiac myxoma Figure 4 | Gross and histopathological characteristics of cardiac myxoma. a | Smooth surface tumour and b | villiform tumour that is more likely to be associated with thromboembolic phenomena. c | Myxoma cells, both singly and in clusters, in a myxoid background. d | Myxoma cells (black arrows) show lost expression of cAMP-dependent protein kinase type 1α regulatory subunit (PRKAR1A) in the setting of Carney complex, whereas background inflammatory cells show retained expression (red arrow). Maleszewski, J. J. et al. (2017) Pathology, imaging, and treatment of cardiac tumours Nat. Rev. Cardiol. doi:10.1038/nrcardio.2017.47