Changes in blood coagulability as it traverses the ischemic limb

Slides:

Advertisements

Similar presentations

Without prejudice Journal of Vascular Surgery

Advertisements

Interface pressure and stiffness of ready made compression stockings: Comparison of in vivo and in vitro measurements Hugo Partsch, MD, Bernhard Partsch,

Association of obesity and metabolic syndrome with the severity and outcome of intermittent claudication Jonathan Golledge, MChir, MA, FRCS, FRACS, Anthony.

Revenue cycle management

Hypertensive extracorporeal limb perfusion (HELP): A new technique for managing critical lower limb ischemia Rodney J. Lane, MD, Mark Phillips, PhD,

Teresa A. Crutchley, MD, Jeffrey D. Pearce, MD, Timothy E

IP219 Functional Popliteal Artery Entrapment Syndrome: A Systematic Review of Diagnosis and Management Niti Shahi, Mariano Arosemena, Jeontaik Kwon,

von Roten I , Madjdpour C , Frascarolo P , Burmeister M. -A

Validation of a method for determination of the ankle-brachial index in the seated position Heather L. Gornik, MD, MHS, Bobby Garcia, BA, Kathy Wolski,

Popliteal entrapment syndrome

Extrinsic compression of the external iliac artery following internal fixation of an acetabular fracture Erin Koelling, MD, Dipankar Mukherjee, MD Journal.

Clinical reliability and utility of skin perfusion pressure measurement in ischemic limbs— Comparison with other noninvasive diagnostic methods Tetsuya.

Prospective evaluation of the relationship between C-reactive protein, D-dimer and progression of peripheral arterial disease Scott E. Musicant, MD,

Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL) trial: A survival prediction model to facilitate clinical decision making Andrew W.

Revision using distal inflow is a safe and effective treatment for ischemic steal syndrome and pathologic high flow after access creation Thomas M. Loh,

Breakthrough: Arthur Blakemore and Arthur Voorhees, Jr

Louis L. Nguyen, MD, MBA, MPH Journal of Vascular Surgery

Nimarta Singh, BA, Kiang Liu, PhD, Lu Tian, ScD, Michael H

A modified calculation of ankle-brachial pressure index is far more sensitive in the detection of peripheral arterial disease Frank Schröder, MD, Nicolas.

New insights into the physiologic basis for intermittent pneumatic limb compression as a therapeutic strategy for peripheral artery disease Ryan D. Sheldon,

Comparison of generic and disease-specific questionnaires for the assessment of quality of life in patients with peripheral arterial disease Marianne.

Does prior administration of enoxaparin influence the effects of levobupivacaine on blood clotting? Assessment using the Thrombelastograph® S.A. Leonard,

Autogenous reconstruction with the lower extremity deep veins: An alternative treatment of prosthetic infection after reconstructive surgery for aortoiliac.

Ankle-Brachial Index Measurement With an Automated Oscillometric Blood Pressure Cuff: Bringing the Ankle-Brachial Index Back to the Bedside Laurence.

Younger women with symptomatic peripheral arterial disease are at increased risk of depressive symptoms Kim G. Smolderen, PhD, John A. Spertus, MD, MPH,

Katharine L. McGinigle, MD, MPH, Corey A. Kalbaugh, MS, MA, William A

Using distal revascularization with interval ligation as the primary treatment of hand ischemia after dialysis access creation Rahim Aimaq, MD, Steven.

Prevention of recurrence of venous ulceration: Randomized controlled trial of class 2 and class 3 elastic compression E. Andrea Nelson, RN, PhD, Douglas.

Profound acute limb ischemia affecting all four limbs following cocaine inhalation Christine M. McMullin, MCRS, Iman Bayat, MRCS, Ed Rytina, FRCPath,

Without prejudice Journal of Vascular Surgery

Collateral artery from arteriovenous malformation of the rectum in a patient with peripheral artery disease Hirotomo Uchiyama, MD, Reiji Hattori, MD,

An analysis of IN.PACT DEEP randomized trial on the limitations of the societal guidelines-recommended hemodynamic parameters to diagnose critical limb.

Combined effects of smoking and peripheral arterial disease on all-cause and cardiovascular disease mortality in a Chinese male cohort Yingyi Luo, MD,

Changing demographics in patients with vascular disease

IP161. Staple Aneurysmorrhaphy of Arteriovenous Fistula Pseudoaneurysm Pending Rupture: A Case Report and Literature Review Peter Lee Journal of Vascular.

Regarding “Endovascular treatment of atherosclerotic popliteal artery disease based on dynamic angiography findings” Jose Antonio Diaz, MD Journal of.

Alexis Carrel's historic leap of faith

Long-term effects of endovascular angioplasty on orthostatic vasocutaneous autoregulation in patients with peripheral atherosclerosis Marc J. Husmann,

The association between elevated ankle systolic pressures and peripheral occlusive arterial disease in diabetic and nondiabetic subjects Victor Aboyans,

Cryopreserved saphenous vein graft in infrainguinal bypass

Outcomes of infrainguinal bypass determined by age in the Vascular Study Group of New England Meghan Dermody, MD, MS, Christopher Homsy, MD, Yuanyuan.

Current accepted hemodynamic criteria for critical limb ischemia do not accurately stratify patients at high risk for limb loss Raghuveer Vallabhaneni,

Therapeutic angiogenesis in Buerger's disease (thromboangiitis obliterans) patients with critical limb ischemia by autologous transplantation of bone.

Preoperative Ankle-Brachial Index Stratification for Patients With Peripheral Arterial Disease Yifei Sun, MD, Ashish Singal, PhD, Rumi Faizer, MD, Alan.

The future of vascular surgery

Natural history of limbs with arterial insufficiency and chronic ulceration treated without revascularization William A. Marston, MD, Stephen W. Davies,

Mortality in patients with premature lower extremity atherosclerosis

IP203. Initial Improvement in Ankle-Brachial Index After Vein Bypass for Rest Pain Predicts Limb Salvage Senthil N. Jayarajan, Adrian C. Vlada, Michael.

Manjit S. Gohel, MB, MRCS, Robin A. J. Windhaber, MSc, MRCS, John F

Compression stockings significantly improve hemodynamic performance in post- thrombotic syndrome irrespective of class or length Christopher R. Lattimer,

Roel H. D. Vaes, MD, Jan H. Tordoir, MD, PhD, Marc R

Reply Journal of Vascular Surgery

Long-term results of combined common femoral endarterectomy and iliac stenting/stent grafting for occlusive disease Robert W. Chang, MD, Philip P. Goodney,

Ramyar Gilani, MD, Roy K. Greenberg, MD, Douglas R. Johnston, MD

Reviewer Acknowledgment

Protamine Enhances Fibrinolysis by Decreasing Clot Strength: Role of Tissue Factor- Initiated Thrombin Generation Vance G. Nielsen, MD The Annals of.

Peripheral atherectomy in TransAtlantic InterSociety Consensus type C femoropopliteal lesions for limb salvage Andrea E. Yancey, MD, David J. Minion,

The toe-brachial index in the diagnosis of peripheral arterial disease

Journal of Vascular Surgery

The influence of aortic cuffs and iliac limb extensions on the outcome of endovascular abdominal aortic aneurysm repair Roel Hobo, MSc, Robert J.F. Laheij,

Lower extremity artery stenosis distribution in an unselected elderly population and its relation to a reduced ankle-brachial index Johan Wikström, MD,

Regarding “Vascular abnormalities in patients with neurofibromatosis syndrome type I: Clinical spectrum, management, and results” John B. Chang, MD,

Tissue (muscle) oxygen saturation (StO2): A new measure of symptomatic lower- extremity arterial disease Anthony J Comerota, MD, Richard C Throm, BA,

Altered fibrin clot structure and function in the healthy first-degree relatives of subjects with intermittent claudication Neeraj Bhasin, MD, Robert.

Karthikeshwar Kasirajan, MD, Peter A Schneider, MD

Ioannis Prionidis, MD, Tom F. Browne Journal of Vascular Surgery

IP193. Controlled Compression Treatment With a Constant Resting Pressure and High Peak Working Pressure Toby Lundh Journal of Vascular Surgery Volume.

Fibromuscular dysplasia with multiple visceral artery involvement

Association of clinical attributes and treadmill walking performance in patients with claudication due to peripheral artery disease Eric P. Brass, MD,

Gabor Libertiny, FRCS, Linda Hands, MS, FRCS

Presentation transcript:

Changes in blood coagulability as it traverses the ischemic limb V.K Shankar, FRCS(Ed), S Ray Chaudhury, S FRCS(Eng), M.C Uthappa, FRCS(Glas), FRCR, A Handa, FRCS(Eng), FRCS(Ed), L.J Hands, MS, FRCS(Eng) Journal of Vascular Surgery Volume 39, Issue 5, Pages 1033-1042 (May 2004) DOI: 10.1016/j.jvs.2003.12.039

Fig 1 Thromboelastography values (mean) for blood samples obtained during transfemoral angiography. R, Reaction time (time to initial fibrin formation); K, dynamics of clot formation; Angle, acceleration of fibrin buildup and cross-linking (clot strengthening); MA, maximum amplitude (ultimate clot strength); CI, coagulation index (overall coagulation status); ABPI, ankle-brachial pressure index; TFA, transfemoral angiography. Journal of Vascular Surgery 2004 39, 1033-1042DOI: (10.1016/j.jvs.2003.12.039)

Fig 2 Coagulation state of each blood sample. R, Reaction time (time to initial fibrin formation); K, dynamics of clot formation; Angle, acceleration of fibrin buildup and cross-linking (clot strengthening); MA, maximum amplitude (ultimate clot strength); CI, coagulation index (overall coagulation status); LY30, percent lysis at 30 minutes after MA; LY60, percent lysis at 60 minutes after MA; G, clot firmness as shear elastic modulus; EPL, estimated percent lysis; A, current amplitude. Journal of Vascular Surgery 2004 39, 1033-1042DOI: (10.1016/j.jvs.2003.12.039)

Fig 3 Severity of iliac disease and change in reaction (R) time. Journal of Vascular Surgery 2004 39, 1033-1042DOI: (10.1016/j.jvs.2003.12.039)

Fig 4 Severity of iliac disease and change in maximum amplitude (MA). Journal of Vascular Surgery 2004 39, 1033-1042DOI: (10.1016/j.jvs.2003.12.039)

Fig 5 Severity of iliac disease and change in coagulation index (CI). Journal of Vascular Surgery 2004 39, 1033-1042DOI: (10.1016/j.jvs.2003.12.039)

Fig 6 Correlation between change in coagulation index (CI) and ankle-brachial pressure index (ABPI). Journal of Vascular Surgery 2004 39, 1033-1042DOI: (10.1016/j.jvs.2003.12.039)

Fig 7 Correlation between change in maximum amplitude (MA) and ankle-brachial pressure index (ABPI) across ischemic limb. Journal of Vascular Surgery 2004 39, 1033-1042DOI: (10.1016/j.jvs.2003.12.039)

Fig 8 Correlation between change in maximum amplitude (MA) across ischemic limb and angiographic severity of infrainguinal atherosclerotic disease. A-V, arteriovenous. Journal of Vascular Surgery 2004 39, 1033-1042DOI: (10.1016/j.jvs.2003.12.039)