Localized cutaneous argyria

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Presentation transcript:

Localized cutaneous argyria Alexandra C. Hristov, MD, Whitney A. High, MD, JD, Loren E. Golitz, MD Journal of the American Academy of Dermatology Volume 65, Issue 3, Pages 660-661 (September 2011) DOI: 10.1016/j.jaad.2010.05.016 Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Brown-black granules coat dermal elastic and collagen fibers (A) and basement membrane of eccrine sweat glands (B). An adjacent ill-defined aggregate of histiocytes contains numerous crystalline, silica fragments (C). (Hematoxylin-eosin stain; original magnification: A, B, and C ×600.) Journal of the American Academy of Dermatology 2011 65, 660-661DOI: (10.1016/j.jaad.2010.05.016) Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 A, Dark field microscopy reveals small, white, refractile granules deposited on elastic and collagen fibers. B, Scanning electron microscopy demonstrates small particles on elastic and collagen fibers. C, Energy-dispersive spectroscopy identifies the particles as minute fragments of silver and copper and confirms admixed silica. (A, Hematoxylin-eosin stain; B and C, unstained slides; original magnifications: A, ×400; B, ×1500.) Journal of the American Academy of Dermatology 2011 65, 660-661DOI: (10.1016/j.jaad.2010.05.016) Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions