Incremental predictive value of CR after repetitive squatting exercise and FC from cardiopulmonary testing exercise results over clinical (red) and echocardiographic.

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Incremental predictive value of CR after repetitive squatting exercise and FC from cardiopulmonary testing exercise results over clinical (red) and echocardiographic (green) information by likelihood ratio analysis expressed as χ 2 values (y-axis) for predi... Incremental predictive value of CR after repetitive squatting exercise and FC from cardiopulmonary testing exercise results over clinical (red) and echocardiographic (green) information by likelihood ratio analysis expressed as χ 2 values (y-axis) for prediction of adverse clinical events. Basal clinical model (first red column) consisted of age, NT-proBNP levels and NYHA functional class, while basal echocardiographic model (first green column) consisted of age, E/E' ratio and LV EF obtained at rest. CR, contractile reserve; E/E', ratio of pulsed-wave Doppler-derived early diastolic transmitral flow and tissue Doppler-derived early diastolic velocity obtained from the lateral mitral annulus; EF, ejection fraction; FC, functional capacity; LV, left ventricular; NT-proBNP, N-terminal pro-B-type natriuretic peptide; NYHA, New York Heart Association. Krunoslav Michael Sveric et al. Open Heart 2018;5:e000733 ©2018 by British Cardiovascular Society